ArticleProceedings of the National Academy of Sciences of the United States of America2014
Large effect of membrane tension on the fluid-solid phase transitions of two-component phosphatidylcholine vesicles.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 66 citations in OpenAlex.
- Electrodeformation of DMPC vesicle membranes near the main phase transition.Biophysical journal · 2025Article
- Article
- Methyl-β-cyclodextrin asymmetrically extracts phospholipid from bilayers, granting tunable control over differential stress in lipid vesicles.Soft matter · 2024Article
- Flower-shaped 2D crystals grown in curved fluid vesicle membranes.Nature communications · 2024Article
- Fluid-gel coexistence in lipid membranes under differential stress.Biophysical journal · 2022Article
- Systematic measurements of interleaflet friction in supported bilayers.Biophysical journal · 2022Article
- Curvature-Mediated Forces on Elastic Inclusions in Fluid Interfaces.Langmuir : the ACS journal of surfaces and colloids · 2022Article
- Polymer-Lipid Hybrid Materials.Chemical reviews · 2021Review
- Switchable positioning of plate-like inclusions in lipid membranes: Elastically mediated interactions of planar colloids in 2D fluids.Science advances · 2021Article
- Imaging non-classical mechanical responses of lipid membranes using molecular rotors.Chemical science · 2020Article
- Nonaxisymmetric Shapes of Biological Membranes from Locally Induced Curvature.Biophysical journal · 2020Article
- Plasma membrane tension regulates eisosome structure and function.Molecular biology of the cell · 2020Article
- Complex Phase Behavior of GUVs Containing Different Sphingomyelins.Biophysical journal · 2019Article
- A new model for lipid monolayer and bilayers based on thermodynamics of irreversible processes.PloS one · 2019Article
- Visualizing Tension and Growth in Model Membranes Using Optical Dyes.Biophysical journal · 2018Article
- DPPC Bilayers in Solutions of High Sucrose Content.Biophysical journal · 2018Article
- The role of gel-phase domains in electroporation of vesicles.Scientific reports · 2018Article
- Critical Concentration of Lecithin Enhances the Antimicrobial Activity of Eugenol against Escherichia coli.Applied and environmental microbiology · 2017Article
- Thermal-driven domain and cargo transport in lipid membranes.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- With or without rafts? Alternative views on cell membranes.BioEssays : news and reviews in molecular, cellular and developmental biology · 2016Review
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Authors and funding
2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Model phospholipid membranes and vesicles have long provided insight into the nature of confined materials and membranes while also providing a platform for drug delivery. The rich thermodynamic behavior and interesting domain shapes in these membranes have previously been mapped in extensive studies that vary temperature and composition; however, the thermodynamic impact of tension on bilayers has been restricted to recent reports of subtly reduced fluid-fluid transition temperatures. In two-component phosphatidylcholine unilamellar vesicles [1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)/1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)], we report a dramatic influence of tension on the fluid-solid transition and resulting phases: At fixed composition, systematic variations in tension produce differently shaped solid domains (striped or irregular hexagons), shift fluid-solid transition temperatures, and produce a triple-point-like intersection of coexistence curves at elevated tensions, about 3 mN/m for 30% DOPC/70% DPPC. Tension therefore represents a potential switch of microstructure in responsive engineered materials; it is an important morphology-determining variable in confined systems, and, in biological membranes, it may provide a means to regulate dynamic structure.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.