Evidence map›Paper›PMID 24344084›Full record

ArticleCirculation2014

Airflow obstruction, lung function, and incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study.

Jingjing Li, Sunil K Agarwal, Alvaro Alonso, Saul Blecker, Alanna M Chamberlain, Stephanie J London, Laura R Loehr, Ann Marie McNeill, Charles Poole, Elsayed Z Soliman and 1 more

Open access · bronzeAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Circulation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 7 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 7 syntheses or guidelines pooled it, 138 citations in OpenAlex.

  1. Pooled it
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  5. European Heart Rhythm Association (EHRA)/European Association of Cardiovascular Prevention and Rehabilitation (EACPR) position paper on how to prevent atrial fibrillation endorsed by the Heart Rhythm Society (HRS) and Asia Pacific Heart Rhythm Society (APHRS).Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2017
    Guideline
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  7. Pooled it
  8. Trial
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Jingjing LiUniversity of North Carolina, Chapel Hill, NC (J.L., L.R.L., A.M.M., C.P., G.H.); Johns Hopkins University, Baltimore, MD (S.K.A.); University of Minnesota, Minneapolis (A.A.); New York University Medical Center, New York (S.B.); Mayo Clinic, Rochester, MN (A.M.C.); National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC (S.J.L.); and Wake Forest University, Winston Salem, NC (E.Z.S.).
Sunil K Agarwal
Alvaro Alonso
Saul Blecker
Alanna M Chamberlain
Stephanie J London
Laura R Loehr
Ann Marie McNeill
Charles Poole
Elsayed Z Soliman
Gerardo Heiss
New York University · USMayo Clinic in Arizona · USNational Institutes of Health · USUniversity of Minnesota · USJohns Hopkins University · USNational Institute of Environmental Health Sciences · US

Funding

CARDIOVASCULAR EPIDEMIOLOGY INSTITUTIONAL TRAININGT32HL007024 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Elizabeth Selvin · 1985 to 2026
$17.5M
Cardiovascular Disease Epidemiology &Prevention TrngT32HL007779 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI PAMELA L. Lutsey, JAMES S PANKOW · 1994 to 2026
$9.3M
ARIC Neurocognitive Study (ARIC-NCS)U01HL096902 · NHLBI · UNIVERSITY OF MINNESOTA · PI LUTSEY, PAMELA L. · 2010 to 2018
$7.4M
Genetic Analyses For Epidemiologic Studies Of Respiratory DiseaseZIAES025045 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LONDON, STEPHANIE · 2009 to 2025
$7.3M
Genetic And Environmental Factors In Childhood Respiratory HealthZIAES049019 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LONDON, STEPHANIE · 2009 to 2025
$6.8M
Genetics and Environment in Adult Respiratory, Allergic and Cardiac diseaseZIAES043012 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LONDON, STEPHANIE · 2009 to 2025
$6.4M
Lung Health Study in the Agricultural Health StudyZIAES102385 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LONDON, STEPHANIE · 2009 to 2025
$6.1M
The Race-Specific Prevalence of Atrial Fibrillation Measured by 48-Hour HolterR01HL116900 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LOEHR, LAURA L · 2013 to 2016
$2.6M
COMMUNITY AND COHORT SURVEILLANCE PROGRAMS-N01HC55015N01HC055015 · HC · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI CHAMBLESS, LLOYD E · 1985 to 2006
$1.1M
CLIN CTR CLIN TRIAL/OBSERVATIONAL STUDY OF WHIN01WH042117 · WH · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI HEISS, GERARDO · 1994 to 2001
$1.0M
Epidemiologic Study of Risk Factors and Biomarkers of Atrial FibrillationRC1HL099452 · NHLBI · UNIVERSITY OF MINNESOTA · PI ALONSO, ALVARO · 2009 to 2010
$897k
COMMUNITY AND COHORT SURVEILLANCE PROGRAMN01HC055016 · HC · BAYLOR COLLEGE OF MEDICINE · PI BALLANTYNE, CHRISTIE M · 1985 to 2000
$785k
AHRQ HHS K08 HS023683Intramural NIH HHS ZIA ES025045Intramural NIH HHS ZIA ES049019Intramural NIH HHS ZIA ES101574Intramural NIH HHS ZIA ES102385NHLBI NIH HHS HHSN268201100007CNHLBI NIH HHS IRC1 HL099452-01NHLBI NIH HHS L30 HL110223NHLBI NIH HHS N01 HC055015NHLBI NIH HHS N01 HC055018NHLBI NIH HHS N01-HC-55015NHLBI NIH HHS N01-HC-55016NHLBI NIH HHS N01-HC-55018NHLBI NIH HHS N01-HC-55019NHLBI NIH HHS N01-HC-55020NHLBI NIH HHS N01-HC-55021NHLBI NIH HHS N01-HC-55022NHLBI NIH HHS R01 HL116900NHLBI NIH HHS R21 HL109611NHLBI NIH HHS RC1 HL099452NHLBI NIH HHS T32 HL007024NHLBI NIH HHS T32HL007024NHLBI NIH HHS T32 HL007779NHLBI NIH HHS T32-HL-007779NHLBI NIH HHS U01 HL096902WHI NIH HHS N01 WH042117
6 · The paper itself

Abstract

backgroundReduced low forced expiratory volume in 1 second (FEV1) is reportedly associated with an increased risk of atrial fibrillation (AF). Extant reports do not provide separate estimates for never smokers or for blacks, who incongruously have lower AF incidence than whites. METHODS AND

resultsWe examined 15 004 middle-aged blacks and whites enrolled in the Atherosclerosis Risk in Communities (ARIC) cohort study. Standardized spirometry data were collected at the baseline examination. Incident AF was identified from the first among the following: International Classification of Diseases codes for AF on hospital discharge records or death certificates or 12-lead ECGs performed during 3 triennial follow-up visits. Over an average follow-up of 17.5 years, a total of 1691 participants (11%) developed new-onset AF. The rate of incident AF was inversely associated with FEV1 in each of the 4 race and sex groups. After multivariable adjustment for traditional cardiovascular disease risk factors and height, hazard ratios of AF comparing the lowest with the highest quartile of FEV1 were 1.37 (95% confidence interval, 1.02-1.83) for white women, 1.49 (95% confidence interval, 1.16-1.91) for white men, 1.63 (95% confidence interval, 1.00-2.66) for black women, and 2.36 (95% confidence interval, 1.30-4.29) for black men. The above associations were observed across all smoking status categories. Moderate/severe airflow obstruction (FEV1/forced vital capacity <0.70 and FEV1 < 80% of predicted value) was also associated with higher AF incidence.

conclusionsIn this large population-based study with a long-term follow-up, reduced FEV1 and obstructive respiratory disease were associated with a higher AF incidence after adjustment for measured confounders.

Indexed as

Atrial FibrillationBlack PeopleCohort StudiesFemaleFollow-Up StudiesForced Expiratory VolumeHumansIncidenceLongitudinal StudiesLungLung Diseases, ObstructiveMaleMiddle AgedProspective StudiesRespiratory Function TestsRisk Factorsatrial fibrillationforced expiratory volumepulmonary disease, chronic obstructiverespiratory physiological phenomenarisk factorsvital capacity

Identifiers

PMID24344084
PMCPMC3963836
OpenAlexW2089442743

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.