ArticleCerebral cortex (New York, N.Y. : 1991)2015
Preferential detachment during human brain development: age- and sex-specific structural connectivity in diffusion tensor imaging (DTI) data.
Article in Cerebral cortex (New York, N.Y. : 1991), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
69 citing papers in PubMed, 1 synthesis or guideline pooled it.
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- Predicting Surgery Targets in Temporal Lobe Epilepsy through Structural Connectome Based Simulations.PLoS computational biology · 2015Trial
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- From behavioral profiles to neural scaffolds: cortico-striatal integrity predicts longitudinal stability and transition in psychological adaptability during early adulthood.Psychological medicine · 2026Article
- Sex differences in the development of object imagery abilities across age groups.Scientific reports · 2026Article
- Deterministic versus Probabilistic Tractography: Impact on White Matter Bundle Shape.bioRxiv : the preprint server for biology · 2025Article
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- Dynamic fluctuations of intrinsic brain activity are associated with consistent topological patterns in puberty and are biomarkers of neural maturation.Network neuroscience (Cambridge, Mass.) · 2025Article
- Evolution of Core Symptoms of Depression Disorders Among Chinese Adolescents Across Different Grades.Depression and anxiety · 2025Article
- Hemochromatosis neural archetype reveals iron disruption in motor circuits.Science advances · 2024Article
- Asymmetry of the Frontal Aslant Tract Depends on Handedness.AJNR. American journal of neuroradiology · 2024Article
- Brain signaling becomes less integrated and more segregated with age.bioRxiv : the preprint server for biology · 2024Article
- Transcutaneous auricular vagus nerve stimulation for long-term post-stroke cognitive impairment: a DTI case report.Frontiers in human neuroscience · 2024Article
- Interoceptive brain network mechanisms of mindfulness-based training in healthy adolescents.Frontiers in psychology · 2024Article
- Brain signaling becomes less integrated and more segregated with age.Network neuroscience (Cambridge, Mass.) · 2024Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Human brain maturation is characterized by the prolonged development of structural and functional properties of large-scale networks that extends into adulthood. However, it is not clearly understood which features change and which remain stable over time. Here, we examined structural connectivity based on diffusion tensor imaging (DTI) in 121 participants between 4 and 40 years of age. DTI data were analyzed for small-world parameters, modularity, and the number of fiber tracts at the level of streamlines. First, our findings showed that the number of fiber tracts, small-world topology, and modular organization remained largely stable despite a substantial overall decrease in the number of streamlines with age. Second, this decrease mainly affected fiber tracts that had a large number of streamlines, were short, within modules and within hemispheres; such connections were affected significantly more often than would be expected given their number of occurrences in the network. Third, streamline loss occurred earlier in females than in males. In summary, our findings suggest that core properties of structural brain connectivity, such as the small-world and modular organization, remain stable during brain maturation by focusing streamline loss to specific types of fiber tracts.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.