ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2014
Heart rate variability associates with asymptomatic coronary atherosclerosis.
Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 25 citations in OpenAlex.
- Comparative effects of electronic and traditional cigarette use on pulmonary function, autonomic regulation, and exercise capacity in young adults.Irish journal of medical science · 2026Article
- Similar Patterns of Dysautonomia in Myalgic Encephalomyelitis/Chronic Fatigue and Post-COVID-19 Syndromes.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024Article
- Cardiovagal Function Measured by the Deep Breathing Test: Relationships With Coronary Atherosclerosis.Journal of the American Heart Association · 2022Article
- The effects of clinical and angiographic aspects of coronary artery disease on the cardiac autonomic function: a single-center prospective cohort study.American journal of cardiovascular disease · 2021Article
- Can short-term heart rate variability predict coronary artery disease in patients undergoing elective coronary angiography due to typical chest pain?Journal of clinical and translational research · 2020Article
- Heart rate variability and incidence of depression during the first six months following first myocardial infarction.Neuropsychiatric disease and treatment · 2019Article
- Heart rate variability among women undergoing in vitro fertilization treatment: Its predictive ability for pregnancy.PloS one · 2018Observational
- Anxiety Level and Cardiac Autonomic Modulations in Coronary Artery Disease and Cardiac Syndrome X Patients.PloS one · 2017Article
- Smoking-Suppressed Heart Rate Recovery in Young Male College Students Who Regularly Exercised.Iranian journal of public health · 2015Article
- Changes in Heart Rate Variability Parameters after Elective Percutaneous Coronary Intervention.The journal of Tehran Heart Center · 2015Article
- Other factors may effect the relationship between heart rate variability indices and coronary atherosclerosis.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2014Article
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7 authors at 4 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeHeart rate variability (HRV) becomes impaired in symptomatic coronary artery disease (CAD), particularly, after myocardial infarction. The mechanism how CAD results in impairment of cardiac autonomic regulation is not known. Whether it results rather from coronary atherosclerosis itself than myocardial ischemia and myocardial injury has remained elusive.
methodsQuantitative coronary angiography was performed in 30 subjects without history of myocardial ischemia, but with high familial risk for CAD. HRV was measured from 24-h ambulatory ECG recordings in time and frequency domain and also non-linear HRV variables SD1 and SD2 in Poincare plot were calculated. Myocardial ischemia was excluded by Tc-99m sestamibi scintigraphy at rest and during exercise.
resultsCoronary angiography revealed mean diameter stenosis of 32 ± 19 % in left anterior descending coronary artery, 26 ± 16 % in left circumflex coronary artery and 25 ± 20 % in right coronary artery. An inverse correlation was found between pNN50 and global severity of coronary artery diameter stenosis (r = -0.415, p < 0.05). Correspondingly, power of HF spectral component correlated negatively with global extent of coronary atherosclerosis (r = -0.366, p < 0.05). In Poincare plot, SD1/SD2 ratio correlated with global extent (r = -0.394, p < 0.05) and global burden (r = -0.388, p < 0.05) of coronary arteries.
conclusionsThe severity and extent of coronary atherosclerosis were related to a shift of cardiac autonomic regulation towards sympathetic predominance in asymptomatic subjects without evidence of myocardial ischemia.
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