ArticleBiological psychiatry2014
Dissociated effects of anticipating smoking versus monetary reward in the caudate as a function of smoking abstinence.
Article in Biological psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 73 citations in OpenAlex.
- The effect and neural changes underlying mindfulness meditation training in patients with comorbid internet gaming disorder and depression: A randomized clinical trial.Translational psychiatry · 2026Trial
- Neural Signatures of Cognitive Flexibility and Reward Sensitivity Following Nicotinic Receptor Stimulation in Dependent Smokers: A Randomized Trial.JAMA psychiatry · 2017Trial
- rTMS Suppresses Tobacco Craving via Enhanced Prefronto-Striato-Thalamic Connectivity.Addiction biology · 2026Article
- Tobacco deprivation impairs metacognitive accuracy and cognitive flexibility.Psychopharmacology · 2025Article
- From Smoking to Vaping: The Motivation for E-cigarette Use at the Neurobiological Level-A Functional Magnetic Resonance Imaging Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Repetitive transcranial magnetic stimulation reduces smoking cravings by decreasing cerebral blood flow in the dorsolateral prefrontal cortex.Brain communications · 2025Article
- Comparative analysis of cortical anatomy in male participants with internet gaming disorder or tobacco use disorder: Insights from normative modeling.Journal of behavioral addictions · 2024Article
- Machine Learning of Functional Connectivity to Biotype Alcohol and Nicotine Use Disorders.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Article
- Testing the efficacy of real-time fMRI neurofeedback for training people who smoke daily to upregulate neural responses to nondrug rewards.Cognitive, affective & behavioral neuroscience · 2023Article
- Association between cigarette smoking and Parkinson's disease: a neuroimaging study.Therapeutic advances in neurological disorders · 2022Article
- Anhedonia in tobacco withdrawal among African-American smokers.Experimental and clinical psychopharmacology · 2021Article
- Dynamic Neuroimaging Biomarkers of Smoking in Young Smokers.Frontiers in psychiatry · 2020Article
- Habenular and striatal activity during performance feedback are differentially linked with state-like and trait-like aspects of tobacco use disorder.Science advances · 2019Article
- A Novel Hierarchical LATER Process Model: Evaluating Latent Sources of Variation in Reaction Times of Adult Daily Smokers.Frontiers in psychiatry · 2019Article
- Is brain response to food rewards related to overeating? A test of the reward surfeit model of overeating in children.Appetite · 2018Article
- The Acute Effects of a Dopamine D3 Receptor Preferring Agonist on Motivation for Cigarettes in Dependent and Occasional Cigarette Smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018Article
- Functional Neurocircuits and Neuroimaging Biomarkers of Tobacco Use Disorder.Trends in molecular medicine · 2018Review
- The Effects of Smoking Abstinence on Incentivized Spatial Working Memory.Substance use & misuse · 2018Article
- Neurobiology of social reward valuation in adults with a history of anorexia nervosa.PloS one · 2018Article
- Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction.BMC genomics · 2017Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundTheories of addiction suggest that chronic smoking may be associated with both hypersensitivity to smoking and related cues and hyposensitivity to alternative reinforcers. However, neural responses to smoking and nonsmoking rewards are rarely evaluated within the same paradigm, leaving the extent to which both processes operate simultaneously uncertain. Behavioral evidence and theoretical models suggest that dysregulated reward processing may be more pronounced during deprivation from nicotine, but neuroimaging evidence on the effects of deprivation on reward processing is limited. The current study examined the impact of deprivation from smoking on neural processing of both smoking and monetary rewards.
methodsTwo separate functional magnetic resonance imaging scans were performed in 38 daily smokers, one after smoking without restriction and one following 24 hours of abstinence. A rewarded guessing task was conducted during each scan to evaluate striatal blood oxygen level-dependent response during anticipation of both smoking and monetary rewards.
resultsA significant reward type by abstinence interaction was observed in the bilateral caudate and medial prefrontal cortex during reward anticipation. The blood oxygen level-dependent response to anticipation of smoking reward was significantly higher and anticipation of monetary rewards was significantly lower during abstinence compared with nonabstinence. Attenuation of monetary reward-related activation during abstinence was significantly correlated with abstinence-induced increases in craving and withdrawal.
conclusionsThese results provide the first direct evidence of dissociated effects of smoking versus monetary rewards as a function of abstinence. The findings suggest an important neural pathway that may underlie the choice to smoke in lieu of alternative reinforcement during a quit attempt.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.