ReviewDevelopment and psychopathology2013
Developmental mechanisms in the prodrome to psychosis.
Review in Development and psychopathology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Personality domains in early stages of psychosis: a systematic review and meta-analysis.European archives of psychiatry and clinical neuroscience · 2026Pooled it
- A systematic review and meta-analysis of the impact of relaxation techniques to reduce burden of disease in patients with psychotic disorders.Scientific reports · 2026Pooled it
- Polygenic risk meets early trauma: toward a neuropsychodevelopmental model of schizophrenia.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Right hippocampal volume and attenuated psychotic symptoms distinguish subgroups of youth with common patterns of temporoparietal effective connectivity.Brain structure & function · 2026Article
- Social withdrawal and hippocampal volume among adolescents at clinical high risk for psychosis and healthy comparisons: The moderating role of neighborhood residential stability.Schizophrenia research · 2026Article
- Understanding the Psychosis Spectrum Using a Hierarchical Model of Social Cognition.Schizophrenia bulletin · 2024Article
- Developmental perspectives on the origins of psychotic disorders: The need for a transdiagnostic approach.Development and psychopathology · 2024Review
- Relations of Lifetime Perceived Stress and Basal Cortisol With Hippocampal Volume Among Healthy Adolescents and Those at Clinical High Risk for Psychosis: A Structural Equation Modeling Approach.Biological psychiatry · 2024Article
- Aspects of Area Deprivation Index in Relation to Hippocampal Volume Among Children.JAMA network open · 2024Article
- The reliability and validity of the revised Green et al. paranoid thoughts scale in individuals at clinical high-risk for psychosis.Acta psychiatrica Scandinavica · 2023Article
- Equity in Mental Health Services for Youth at Clinical High Risk for Psychosis: Considering Marginalized Identities and Stressors.Evidence-based practice in child and adolescent mental health · 2022Article
- Translating RDoC to Real-World Impact in Developmental Psychopathology: A Neurodevelopmental Framework for Application of Mental Health Risk Calculators.Development and psychopathology · 2021Article
- A Potential Interface between the Kynurenine Pathway and Autonomic Imbalance in Schizophrenia.International journal of molecular sciences · 2021Review
- First episode psychosis: register-based study of comorbid psychiatric disorders and medications before and after.European archives of psychiatry and clinical neuroscience · 2021Observational
- Acute Physiological and Psychological Stress Response in Youth at Clinical High-Risk for Psychosis.Frontiers in psychiatry · 2021Article
- Timing of menarche and abnormal hippocampal connectivity in youth at clinical-high risk for psychosis.Psychoneuroendocrinology · 2020Article
- Cognitive behaviour therapy for anxiety in adolescent with early prodromal of psychosis at boarding school.BMC nursing · 2019Article
- BDNF overexpression prevents cognitive deficit elicited by adolescent cannabis exposure and host susceptibility interaction.Human molecular genetics · 2017Article
- HPA-axis function and grey matter volume reductions: imaging the diathesis-stress model in individuals at ultra-high risk of psychosis.Translational psychiatry · 2016Article
- Neurodevelopmental Genomic Strategies in the Study of the Psychosis Spectrum.Nebraska Symposium on Motivation. Nebraska Symposium on Motivation · 2016Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Psychotic disorders continue to be among the most disabling and scientifically challenging of all mental illnesses. Accumulating research findings suggest that the etiologic processes underlying the development of these disorders are more complex than had previously been assumed. At the same time, this complexity has revealed a wider range of potential options for preventive intervention, both psychosocial and biological. In part, these opportunities result from our increased understanding of the dynamic and multifaceted nature of the neurodevelopmental mechanisms involved in the disease process, as well as the evidence that many of these entail processes that are malleable. In this article, we review the burgeoning research literature on the prodrome to psychosis, based on studies of individuals who meet clinical high risk criteria. This literature has examined a range of factors, including cognitive, genetic, psychosocial, and neurobiological. We then turn to a discussion of some contemporary models of the etiology of psychosis that emphasize the prodromal period. These models encompass the origins of vulnerability in fetal development, as well as postnatal stress, the immune response, and neuromaturational processes in adolescent brain development that appear to go awry during the prodrome to psychosis. Then, informed by these neurodevelopmental models of etiology, we turn to the application of new research paradigms that will address critical issues in future investigations. It is expected that these studies will play a major role in setting the stage for clinical trials aimed at preventive intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.