Evidence map›Paper›PMID 24342570›Full record

ArticleJournal of magnetic resonance (San Diego, Calif. : 1997)2014

Response to Commentary on "The influence of lung airways branching structure and diffusion time on measurements and models of short-range 3He gas MR diffusion".

Juan Parra-Robles, Jim M Wild

Abstract readComment
PubMed Publisher
In one paragraph

Article in Journal of magnetic resonance (San Diego, Calif. : 1997), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Functional imaging of the lungs with gas agents.Journal of magnetic resonance imaging : JMRI · 2016
    Review
  2. Optically polarizedReviews of modern physics
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Juan Parra-RoblesUnit of Academic Radiology, University of Sheffield, United Kingdom. Electronic address: j.parra-robles@sheffield.ac.uk.
Jim M WildUnit of Academic Radiology, University of Sheffield, United Kingdom.

Funding

Department of Health NIHR-RP-R3-12-027
6 · The paper itself

Abstract

Our extensive investigation of the cylinder model theory through numerical modelling and purpose-designed experiments has demonstrated that it does produce inaccurate estimates of airway dimensions at all diffusion times currently used. This is due to a variety of effects: incomplete treatment of non-Gaussian effects, finite airway size, branching geometry, background susceptibility gradients and diffusion time dependence of the (3)He MR diffusion behaviour in acinar airways. The cylinder model is a good starting point for the development of a lung morphometry technique from (3)He diffusion MR but its limitations need to be understood and documented in the interest of reliable clinical interpretation.

Indexed as

HeliumDiffusion Magnetic Resonance ImagingHumansLungHelium(3)He Diffusion MRLung morphometrymodel validation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.