Evidence map›Paper›PMID 24342564›Full record

ReviewNeuroscience2014

Emerging epigenetic mechanisms of long non-coding RNAs.

K Schaukowitch, T-K Kim

Abstract readReview
In one paragraph

Review in Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.

  1. Pooled it
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

K SchaukowitchThe University of Texas Southwestern Medical Center, Department of Neuroscience, 5323 Harry Hines Boulevard, Dallas, TX 75390-9111, United States.
T-K KimThe University of Texas Southwestern Medical Center, Department of Neuroscience, 5323 Harry Hines Boulevard, Dallas, TX 75390-9111, United States. Electronic address: taekyung.kim@utsouthwestern.edu.
The University of Texas Southwestern Medical Center · US

Funding

Basic Science Training Program in the Neurobiology of Mental IllnessT32MH076690 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI TAMMINGA, CAROL A · 2007 to 2017
$2.3M
The epigenetic mechanism of enhancer RNA in behavioral plasticityR01NS085418 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI KIM, TAE-KYUNG · 2013 to 2017
$1.7M
NIMH NIH HHS T32-MH76690NINDS NIH HHS 1R01NS085418NINDS NIH HHS R01 NS085418
6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) have been increasingly appreciated as an integral component of gene regulatory networks. Genome-wide features of their origin and expression patterns ascribed a prominent role for lncRNAs to the regulation of protein-coding genes, and also suggest a potential link to many human diseases. Recent studies have begun to unravel the intricate regulatory mechanism of lncRNAs occurring at multiple levels. The brain is one of the richest sources of lncRNAs, many of which have already shown a close relationship with genes or genetic loci implicated in a wide range of neurological disorders. This review describes recently emerging mechanistic principles of lncRNA functions to provide neuroscientists with molecular insights that will help future research on lncRNAs in the brain.

Indexed as

Epigenesis, GeneticAnimalsBrainHumansRNA, Long NoncodingRNA, Long Noncodingenhancer RNAsepigeneticslong non-coding RNAs

Identifiers

PMID24342564
PMCPMC3992294
OpenAlexW1979906856

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.