ArticlePLoS neglected tropical diseases2013
Estimating leptospirosis incidence using hospital-based surveillance and a population-based health care utilization survey in Tanzania.
Article in PLoS neglected tropical diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- A systematic review and meta-analysis of the epidemiology of Leptospirosis in HIV uninfected and in people living with HIV from the Southern African Development Community.PLoS neglected tropical diseases · 2022Pooled it
- Epidemiology of leptospirosis in Tanzania: A review of the current status, serogroup diversity and reservoirs.PLoS neglected tropical diseases · 2021Pooled it
- Global Morbidity and Mortality of Leptospirosis: A Systematic Review.PLoS neglected tropical diseases · 2015Pooled it
- Epidemiology of Leptospirosis in Africa: A Systematic Review of a Neglected Zoonosis and a Paradigm for 'One Health' in Africa.PLoS neglected tropical diseases · 2015Pooled it
- Methods for estimating the burden of acute tropical infectious diseases: A scoping review.PLoS neglected tropical diseases · 2026Article
- Derivation and Internal Validation of a Clinical Prediction Model for Diagnosis of Spotted Fever Group Rickettsioses in Northern Tanzania.Open forum infectious diseases · 2025Article
- Detection and Determinants ofPublic health challenges · 2025Article
- Serological Survey ofPathogens (Basel, Switzerland) · 2024Article
- Leptospirosis Cases among Outpatients with Non-Malaria Fever Attending Primary Care Clinics during the Rainy Season in Bobo Dioulasso, Burkina Faso.The American journal of tropical medicine and hygiene · 2024Article
- Facility-based disease surveillance and Bayesian hierarchical modeling to estimate endemic typhoid fever incidence, Kilimanjaro Region, Tanzania, 2007-2018.PLoS neglected tropical diseases · 2022Article
- Prevalence of leptospirosis among patients attending renal and general outpatient clinics in Mulago Hospital, Kampala, Uganda.Scientific reports · 2022Article
- Pathogenic Leptospira Species Are Widely Disseminated among Wild Rodents in Urban Areas of Guangzhou, Southern China.Microorganisms · 2022Article
- Clinical characteristics and prognosis of patient with leptospirosis: A multicenter retrospective analysis in south of China.Frontiers in cellular and infection microbiology · 2022Article
- Prevalence and Factors Associated with Acute Kidney Injury in Sub-Saharan African Adults: A Review of the Current Literature.International journal of nephrology · 2022Review
- Incidence Estimates of Acute Q Fever and Spotted Fever Group Rickettsioses, Kilimanjaro, Tanzania, from 2007 to 2008 and from 2012 to 2014.The American journal of tropical medicine and hygiene · 2021Article
- Incidence of Acute Myocardial Infarction in Northern Tanzania: A Modeling Approach Within a Prospective Observational Study.Journal of the American Heart Association · 2021Observational
- Leptospira Seropositivity in Humans, Livestock and Wild Animals in a Semi-Arid Area of Tanzania.Pathogens (Basel, Switzerland) · 2021Article
- Existence of SimilarPathogens (Basel, Switzerland) · 2021Article
- Epidemiology incidence and geographical distribution of leptospirosis using GIS and its incidence prediction in Iran in 2021.Medical journal of the Islamic Republic of Iran · 2021Article
- Etiologic Agents of Fever of Unknown Origin Among Patients Attending Mnazi Mmoja Hospital, Zanzibar.Journal of community health · 2020Article
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8 authors.
Funding
Abstract
backgroundThe incidence of leptospirosis, a neglected zoonotic disease, is uncertain in Tanzania and much of sub-Saharan Africa, resulting in scarce data on which to prioritize resources for public health interventions and disease control. In this study, we estimate the incidence of leptospirosis in two districts in the Kilimanjaro Region of Tanzania. METHODOLOGY/PRINCIPAL
findingsWe conducted a population-based household health care utilization survey in two districts in the Kilimanjaro Region of Tanzania and identified leptospirosis cases at two hospital-based fever sentinel surveillance sites in the Kilimanjaro Region. We used multipliers derived from the health care utilization survey and case numbers from hospital-based surveillance to calculate the incidence of leptospirosis. A total of 810 households were enrolled in the health care utilization survey and multipliers were derived based on responses to questions about health care seeking in the event of febrile illness. Of patients enrolled in fever surveillance over a 1 year period and residing in the 2 districts, 42 (7.14%) of 588 met the case definition for confirmed or probable leptospirosis. After applying multipliers to account for hospital selection, test sensitivity, and study enrollment, we estimated the overall incidence of leptospirosis ranges from 75-102 cases per 100,000 persons annually. CONCLUSIONS/SIGNIFICANCE: We calculated a high incidence of leptospirosis in two districts in the Kilimanjaro Region of Tanzania, where leptospirosis incidence was previously unknown. Multiplier methods, such as used in this study, may be a feasible method of improving availability of incidence estimates for neglected diseases, such as leptospirosis, in resource constrained settings.
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