ArticlePloS one2013
Serological evidence for multiple strains of canine norovirus in the UK dog population.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 30 citations in OpenAlex.
- Towards Detecting Associations of Canine Astrovirus and Caliciviruses with Health and Living Characteristics of Dogs in Greece.Pathogens (Basel, Switzerland) · 2025Article
- Establishment of a Quadruplex RT-qPCR for the Detection of Canine Coronavirus, Canine Respiratory Coronavirus, Canine Adenovirus Type 2, and Canine Norovirus.Pathogens (Basel, Switzerland) · 2024Article
- Development and evaluation of a new luciferase immunosorbent assay to detect GII.6 norovirus-specific IgG in different domestic and wild animals.Frontiers in microbiology · 2023Article
- First report of canine Astrovirus and Sapovirus in Greece, hosting both asymptomatic and gastroenteritis symptomatic dogs.Virology journal · 2022Article
- Human Norovirus Infection in Dogs, Thailand.Emerging infectious diseases · 2020Article
- Faecal Virome Analysis of Wild Animals from Brazil.Viruses · 2019Article
- Animals as Reservoir for Human Norovirus.Viruses · 2019Review
- Genomics Analyses of GIV and GVI Noroviruses Reveal the Distinct Clustering of Human and Animal Viruses.Viruses · 2019Article
- Identification of canine norovirus in dogs in South Korea.BMC veterinary research · 2018Article
- The First Norovirus Longitudinal Seroepidemiological Study From Sub-Saharan Africa Reveals High Seroprevalence of Diverse Genotypes Associated With Host Susceptibility Factors.The Journal of infectious diseases · 2018Article
- New viruses associated with canine gastroenteritis.Veterinary journal (London, England : 1997) · 2018Review
- Identification of a novel canine norovirus.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2017Article
- Murine norovirus infection in Brazilian animal facilities.Experimental animals · 2017Article
- Seroprevalence for norovirus genogroup II, IV and VI in dogs.Veterinary microbiology · 2017Article
- Evidence for human norovirus infection of dogs in the United kingdom.Journal of clinical microbiology · 2015Article
- Complete genome sequence of canine astrovirus with molecular and epidemiological characterisation of UK strains.Veterinary microbiology · 2015Article
- Article
- Genogroup IV and VI canine noroviruses interact with histo-blood group antigens.Journal of virology · 2014Article
- Norovirus translation requires an interaction between the C Terminus of the genome-linked viral protein VPg and eukaryotic translation initiation factor 4G.The Journal of biological chemistry · 2014Article
- Seroprevalence of canine norovirus in 14 European countries.Clinical and vaccine immunology : CVI · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
Noroviruses are associated with intestinal disease in humans, cows, pigs, mice, and, more recently, dogs. In 2007, the first canine norovirus (CNV) was identified and characterized in Italy. Subsequent studies have identified CNV in stools of dogs from Portugal, Greece, and the United States. To investigate the prevalence of CNV in the UK dog population, 228 canine stool samples were screened for CNV by qPCR, and 396 serum samples were screened for anti-CNV antibodies. qPCR of RNA extracted from canine stool samples did not reveal any CNV-positive samples, based on samples collected from diarrhoeic and control dogs in 2012-2013. CNV virus-like particles to three different CNV strains were produced using recombinant baculoviruses and a seroprevalence screen undertaken. Anti-CNV antibodies were identified at significant levels in canine serum; 38.1% of samples collected between 1999-2001 and 60.1% of samples collected in 2012-2013 were seropositive. The increase in seroprevalence over time (p<0.001) suggests that the CNV strains screened for are becoming more widespread. Variation in seroprevalence to different CNV strains was also identified. Two-thirds of the dogs were seropositive to a single strain, whereas the remaining third were seropositive to two or three of the strains analysed. This study has provided the first evidence that CNV is present in the UK, with seroprevalence identified to multiple circulating strains. This warrants further study and increased awareness of this recently discovered canine virus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.