Evidence map›Paper›PMID 24339911›Full record

ArticlePloS one2013

Association between exposure to environmental tobacco smoke and biomarkers of oxidative stress among patients hospitalised with acute myocardial infarction.

Ian L Megson, Sally J Haw, David E Newby, Jill P Pell

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. The Effects of Smoking on IgE, Oxidative Stress and Haemoglobin Concentration.Asian Pacific journal of cancer prevention : APJCP · 2020
    Article
  6. Article
  7. Review
  8. Cigarette Smoking and Oxidative Stress in Patients with Coronary Artery Disease.Open access Macedonian journal of medical sciences · 2016
    Article
  9. Oxidative Stress in Youth and Adolescents With Elevated Body Mass Index Exposed to Secondhand Smoke.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2016
    Article
  10. Article
  11. Article
  12. Article
  13. Antioxidants in Cardiovascular Therapy: Panacea or False Hope?Frontiers in cardiovascular medicine · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Ian L MegsonFree Radical Research Facility, Department of Diabetes and Cardiovascular Science, University of Highlands and Islands, Inverness, United Kingdom.
Sally J Haw
David E Newby
Jill P Pell
University of Edinburgh · GBUniversity of Glasgow · GBUniversity of Stirling · GBUniversity of the Highlands and Islands · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine whether exposure to environmental tobacco smoke was associated with oxidative stress among patients hospitalised for acute myocardial infarction.

designAn existing cohort study of 1,261 patients hospitalised for acute myocardial infarction.

settingNine acute hospitals in Scotland.

participantsSixty never smokers who had been exposed to environmental tobacco smoke (admission serum cotinine ≥3.0 ng/mL) were compared with 60 never smokers who had not (admission serum cotinine ≤0.1 ng/mL).

interventionNone.

main outcome measuresThree biomarkers of oxidative stress (protein carbonyl, malondialdehyde (MDA) and oxidised low-density lipoprotein (ox-LDL)) were measured on admission blood samples and adjusted for potential confounders.

resultsAfter adjusting for baseline differences in age, sex and socioeconomic status, exposure to environmental tobacco smoke was associated with serum concentrations of both protein carbonyl (beta coefficient 7.96, 95% CI 0.76, 15.17, p = 0.031) and MDA (beta coefficient 10.57, 95% CI 4.32, 16.81, p = 0.001) but not ox-LDL (beta coefficient 2.14, 95% CI -8.94, 13.21, p = 0.703).

conclusionsExposure to environmental tobacco smoke was associated with increased oxidative stress. Further studies are requires to explore the role of oxidative stress in the association between environmental tobacco smoke and myocardial infarction.

Indexed as

HospitalizationAcute DiseaseAgedBiomarkersEnvironmental ExposureFemaleHumansLipoproteins, LDLMaleMalondialdehydeMiddle AgedMultivariate AnalysisMyocardial InfarctionOxidative StressProtein CarbonylationSmokeBiomarkersLipoproteins, LDLMalondialdehydeoxidized low density lipoproteinSmoke

Identifiers

PMID24339911
PMCPMC3855195
OpenAlexW2085388858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.