ArticlePloS one2013
Visual impairment as a function of visual acuity in both eyes and its impact on patient reported preferences.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Vision-related quality of life: 12-month aflibercept treatment in patients with treatment-resistant neovascular age-related macular degeneration.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2017Trial
- Patient-reported vision impairment in low luminance relates to visual function in age-related macular degeneration: A MACUSTAR study report.Scientific reports · 2025Article
- Sleep duration and adolescent vision outcomes: evidence from rural China.Preventive medicine reports · 2025Article
- The Spectrum of Functional, Structural, and Patient-Reported Outcomes in Intermediate Age-Related Macular Degeneration: A MACUSTAR Study Report.Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde · 2025Article
- Patient-reported vision impairment in low luminance predicts multiple falls.BMC geriatrics · 2023Article
- Cross-sectional associations of dietary intake with hearing and vision capacities and potential mediation effect of inflammation in older adults: the COGFRAIL study.Aging clinical and experimental research · 2023Article
- Quality of life impact of eye diseases: a Save Sight Registries study.Clinical & experimental ophthalmology · 2022Article
- Health utilities and costs for neuromyelitis optica spectrum disorder.Orphanet journal of rare diseases · 2022Article
- Cost-effectiveness of dexamethasone and triamcinolone for the treatment of diabetic macular oedema in Finland: A Markov-model.Acta ophthalmologica · 2021Article
- Association of Visual Acuity with Eye-Related Quality of Life and Functional Vision Across Childhood Eye Conditions.American journal of ophthalmology · 2021Article
- Impacts of monocular, binocular, and functional visual acuity on vision-related quality of life in patients with type 2 diabetes.Scientific reports · 2021Article
- Quality of Life of Patients with Glaucoma in Slovakia.International journal of environmental research and public health · 2021Article
- Effects of Cataract Surgery on Vision-Related Quality of Life in Patients with Retinitis Pigmentosa and the Predictive Factors of Quality of Life Improvement.BioMed research international · 2021Article
- Frequency of cataract surgery and its impact on visual function-results from the German Gutenberg Health Study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Article
- Feelings, preoperative anxiety, and need for information in patients undergoing intravitreal injections.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Observational
- Association of Visual Impairment With Risk of Incident Dementia in a Women's Health Initiative Population.JAMA ophthalmology · 2020Article
- Article
- Vision-related quality of life considering both eyes: results from the German population-based Gutenberg Health Study (GHS).Health and quality of life outcomes · 2019Article
- The National Eye Institute 25-Item Visual Function Questionnaire (NEI VFQ-25) - reference data from the German population-based Gutenberg Health Study (GHS).Health and quality of life outcomes · 2017Observational
- Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess the impact of VA loss on patient reported utilities taking both eyes into account compared to taking only the better or the worse eye into account.
methodsIn this cross-sectional study 1085 patients and 254 controls rated preferences with the generic health-related (EQ-5D; n = 868) and vision-specific (Vision and Quality of Life Index (VisQoL); n = 837) multi-attribute utility instruments (MAUIs). Utilities were calculated for three levels of VA in the better and worse eyes, as well as for 6 different vision states based on combinations of the better and worse eye VA.
resultsUsing the VisQoL, utility scores decreased significantly with deteriorating vision in both the better and worse eyes when analysed separately. When stratified by the 6 vision states, VisQoL utilities decreased as VA declined in the worse eye despite stable VA in the better eye. Differences in VisQoL scores were statistically significant for cases where the better eye had no vision impairment and the worse seeing fellow eye had mild, moderate or severe vision impairment. In contrast, the EQ-5D failed to capture changes in better or worse eye VA, or any of the six vision states.
conclusionsCalculating utilities based only on better eye VA or using a generic MAUI is likely to underestimate the impact of vision impairment, particularly when the better eye has no or little VA loss and the worse eye is moderately to severely visually impaired. These findings have considerable implications for the assessment of overall visual impairment as well as economic evaluations within eye health.
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