ArticlePLoS biology2013
A versatile class of cell surface directional motors gives rise to gliding motility and sporulation in Myxococcus xanthus.
Article in PLoS biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 47 citations in OpenAlex.
- Milestones in the development ofJournal of bacteriology · 2025Review
- A novel mechanism for bacterial sporulation based on programmed peptidoglycan degradation.bioRxiv : the preprint server for biology · 2025Article
- Visualization of peptidoglycan layer isolated from gliding diderm bacteria,Biophysics and physicobiology · 2025Article
- Iridescent biofilms of Cellulophaga lytica are tunable platforms for scalable, ordered materials.Scientific reports · 2023Article
- Bacterial Outer Membrane Polysaccharide Export (OPX) Proteins Occupy Three Structural Classes with Selective β-Barrel Porin Requirements for Polymer Secretion.Microbiology spectrum · 2022Article
- Dynamic proton-dependent motors power type IX secretion and gliding motility in Flavobacterium.PLoS biology · 2022Article
- Roadmap on emerging concepts in the physical biology of bacterial biofilms: from surface sensing to community formation.Physical biology · 2021Review
- Review
- Establishing rod shape from spherical, peptidoglycan-deficient bacterial spores.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Modulation of bacterial multicellularity via spatio-specific polysaccharide secretion.PLoS biology · 2020Article
- Transcriptome dynamics of theeLife · 2019Article
- Ultrasensitive Response of Developing Myxococcus xanthus to the Addition of Nutrient Medium Correlates with the Level of MrpC.Journal of bacteriology · 2018Article
- Fatty Acid Oxidation Is Required for Myxococcus xanthus Development.Journal of bacteriology · 2018Article
- TheJournal of bacteriology · 2017Article
- Highly Signal-Responsive Gene Regulatory Network Governing Myxococcus Development.Trends in genetics : TIG · 2017Review
- Article
- MicrobeJ, a tool for high throughput bacterial cell detection and quantitative analysis.Nature microbiology · 2016Article
- Two-Component Signal Transduction Systems That Regulate the Temporal and Spatial Expression of Myxococcus xanthus Sporulation Genes.Journal of bacteriology · 2016Review
- Bacterial protein networks: properties and functions.Nature reviews. Microbiology · 2015Review
- Evolution and Design Governing Signal Precision and Amplification in a Bacterial Chemosensory Pathway.PLoS genetics · 2015Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
Eukaryotic cells utilize an arsenal of processive transport systems to deliver macromolecules to specific subcellular sites. In prokaryotes, such transport mechanisms have only been shown to mediate gliding motility, a form of microbial surface translocation. Here, we show that the motility function of the Myxococcus xanthus Agl-Glt machinery results from the recent specialization of a versatile class of bacterial transporters. Specifically, we demonstrate that the Agl motility motor is modular and dissociates from the rest of the gliding machinery (the Glt complex) to bind the newly expressed Nfs complex, a close Glt paralogue, during sporulation. Following this association, the Agl system transports Nfs proteins directionally around the spore surface. Since the main spore coat polymer is secreted at discrete sites around the spore surface, its transport by Agl-Nfs ensures its distribution around the spore. Thus, the Agl-Glt/Nfs machineries may constitute a novel class of directional bacterial surface transporters that can be diversified to specific tasks depending on the cognate cargo and machinery-specific accessories.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.