ReviewWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
Assessing the barriers to image-guided drug delivery.
Review in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 49 citations in OpenAlex.
- Sonoporation for Augmenting Chemotherapy of Pancreatic Ductal Adenocarcinoma.Methods in molecular biology (Clifton, N.J.) · 2020Trial
- A novel auto-fluorescent porphyrin-lipid nanoparticle strategy for CTNNB1 gene silencing in hepatocellular carcinoma.Frontiers in oncology · 2026Article
- Nanotechnology-driven EGCG: bridging antioxidant and therapeutic roles in metabolic and cancer pathways.Nanomedicine (London, England) · 2025Review
- Aerosolized In Vivo 3D Localization of Nose-to-Brain Nanocarrier Delivery Using Multimodality Neuroimaging in a Rat Model-Protocol Development.Pharmaceutics · 2021Article
- Lipoprotein-Like Nanoparticle Carrying Small Interfering RNA Against Spalt-Like Transcription Factor 4 Effectively Targets Hepatocellular Carcinoma Cells and Decreases Tumor Burden.Hepatology communications · 2020Article
- Concurrent visual and acoustic tracking of passive and active delivery of nanobubbles to tumors.Theranostics · 2020Article
- Imaging Nanomedicine-Based Drug Delivery: a Review of Clinical Studies.Molecular imaging and biology · 2018Review
- Cellular Trafficking of Sn-2 Phosphatidylcholine Prodrugs Studied with Fluorescence Lifetime Imaging and Super-resolution Microscopy.Precision nanomedicine · 2018Article
- A Thioacetal Photocage Designed for Dual Release: Application in the Quantitation of Therapeutic Release by Synchronous Reporter Decaging.Chembiochem : a European journal of chemical biology · 2017Article
- Image-Guided Radiotherapy Targets Macromolecules through Altering the Tumor Microenvironment.Molecular pharmaceutics · 2016Article
- Theragnostic ultrasound using microbubbles in the treatment of prostate cancer.Ultrasonography (Seoul, Korea) · 2016Review
- Use of Theranostic Strategies in Myocardial Cavitation-Enabled Therapy.Ultrasound in medicine & biology · 2015Article
- Image-Guided Drug Delivery with Single-Photon Emission Computed Tomography: A Review of Literature.Current drug targets · 2015Review
- Molecular imaging of atherosclerosis with nanoparticle-based fluorinated MRI contrast agents.Nanomedicine (London, England) · 2015Review
- Hollow mesoporous silica nanoparticles for tumor vasculature targeting and PET image-guided drug delivery.Nanomedicine (London, England) · 2015Article
- In vivo anticancer activity of rhomboidal Pt(II) metallacycles.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Positron emission tomography image-guided drug delivery: current status and future perspectives.Molecular pharmaceutics · 2014Review
- Fluorescent imaging of cancerous tissues for targeted surgery.Advanced drug delivery reviews · 2014Review
- Image-guided interventional therapy for cancer with radiotherapeutic nanoparticles.Advanced drug delivery reviews · 2014Review
- A targeted approach to cancer imaging and therapy.Nature materials · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 11 institutions in 3 countries.
Funding
Abstract
Imaging has become a cornerstone for medical diagnosis and the guidance of patient management. A new field called image-guided drug delivery (IGDD) now combines the vast potential of the radiological sciences with the delivery of treatment and promises to fulfill the vision of personalized medicine. Whether imaging is used to deliver focused energy to drug-laden particles for enhanced, local drug release around tumors, or it is invoked in the context of nanoparticle-based agents to quantify distinctive biomarkers that could risk stratify patients for improved targeted drug delivery efficiency, the overarching goal of IGDD is to use imaging to maximize effective therapy in diseased tissues and to minimize systemic drug exposure in order to reduce toxicities. Over the last several years, innumerable reports and reviews covering the gamut of IGDD technologies have been published, but inadequate attention has been directed toward identifying and addressing the barriers limiting clinical translation. In this consensus opinion, the opportunities and challenges impacting the clinical realization of IGDD-based personalized medicine were discussed as a panel and recommendations were proffered to accelerate the field forward.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.