Trial reportDepression and anxiety2014
Perceived social support mediates anxiety and depressive symptom changes following primary care intervention.
Trial report in Depression and anxiety, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00347269 (Coordinated Anxiety Learning and Management), which is not on this map. Cited by 71 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Coordinated Anxiety Learning and Management (CALM): Improving Primary Care Anxiety Outcomes
Who cites it
71 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Associations between loneliness and perceived social support and outcomes of mental health problems: a systematic review.BMC psychiatry · 2018Pooled it
- The impact of a virtual mind-body program on symptoms of depression and anxiety among international English-speaking adults with neurofibromatosis.American journal of medical genetics. Part A · 2024Trial
- Reciprocal and Indirect Effects Among Intervention, Perceived Social Support, and Anxiety Sensitivity Within a Randomized Controlled Trial for Anxiety Disorders.Behavior therapy · 2024Trial
- A Three-Armed Randomized Controlled Trial to Evaluate the Effectiveness, Acceptance, and Negative Effects ofInternational journal of environmental research and public health · 2023Trial
- Cognitive behavioral stress management effects on prenatal anxiety among low-income women.Journal of consulting and clinical psychology · 2022Trial
- Factors Associated with HIV Disclosure Status Among iENGAGE Cohort of New to HIV Care Patients.AIDS patient care and STDs · 2020Trial
- Understanding the Mechanisms of Change in a Lifestyle Intervention for Older Adults.The Gerontologist · 2018Trial
- Social support as the protector of mental health during the COVID-19 pandemic: Population-based longitudinal evidence across pre- and post-vaccine phases.Social psychiatry and psychiatric epidemiology · 2026Article
- The Therapeutic Home Environment for Chronic Diseases: A Transdisciplinary Ecosystem for Achieving Migraine Freedom and Managing Comorbid Anxiety, Insomnia, and Chronic Pain.Healthcare (Basel, Switzerland) · 2026Article
- Assessing the effectiveness of health checkup services in reducing depressive symptoms in older adults with chronic diseases: a community-based pre-post observational study.BMC public health · 2026Observational
- Social support and psychological distress among family caregivers of palliative patients at two rural hospitals in Malawi: a cross-sectional study.BMC palliative care · 2025Article
- Social well-being moderates behavioral therapy response for generalized anxiety disorder.Journal of mood and anxiety disorders · 2025Article
- Emotional experiences, difficulties, and facilitators in patient care of nurses working in surgical units: a qualitative study.BMC nursing · 2025Article
- Gender Differences in Psychosocial Pathways to Depression and Anxiety: Cross-Sectional and Bayesian Causal Network Study.Journal of medical Internet research · 2025Article
- Perceived social support mediates the relationship between self-efficacy and depression/anxiety in patients with cardiovascular disease.Scientific reports · 2025Article
- Article
- Interventions that prevent or reduce perinatal loneliness and its proximal determinants: a restricted scoping review.BMC public health · 2025Article
- Influence of symptom burden on social alienation in lung cancer patients receiving chemotherapy: the chain mediating effect of perceived social support and positive psychological capital.BMC psychology · 2025Article
- Article
- Loneliness, social support, and social networks: urban-rural variation and links to wellbeing in Scotland.Journal of public health (Berlin, Germany) · 2025Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundThe current study tested whether perceived social support serves as a mediator of anxiety and depressive symptom change following evidence-based anxiety treatment in the primary care setting. Gender, age, and race were tested as moderators.
methodsData were obtained from 1004 adult patients (age M = 43, SD = 13; 71% female; 56% White, 20% Hispanic, 12% Black) who participated in a randomized effectiveness trial (coordinated anxiety learning and management [CALM] study) comparing evidence-based intervention (cognitive-behavioral therapy and/or psychopharmacology) to usual care in the primary care setting. Patients were assessed with a battery of questionnaires at baseline, as well as at 6, 12, and 18 months following baseline. Measures utilized in the mediation analyses included the Abbreviated Medical Outcomes (MOS) Social Support Survey, the Brief Symptom Index (BSI)-Somatic and Anxiety subscales, and the Patient Health Questionnaire (PHQ-9).
resultsThere was a mediating effect over time of perceived social support on symptom change following treatment, with stronger effects for 18-month depression than anxiety. None of the mediating pathways were moderated by gender, age, or race.
conclusionsPerceived social support may be central to anxiety and depressive symptom changes over time with evidence-based intervention in the primary care setting. These findings possibly have important implications for development of anxiety interventions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.