Trial reportMagnetic resonance in medicine2014
Whole-brain three-dimensional T2-weighted BOLD functional magnetic resonance imaging at 7 Tesla.
Trial report in Magnetic resonance in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 47 citations in OpenAlex.
- Large-Vessel Venous Signal Confounds Apparent Amygdala Activation in BOLD fMRI.bioRxiv : the preprint server for biology · 2026Article
- Whole-cerebrum guanidino and amide CEST mapping at 3 T by a 3D stack-of-spirals gradient echo acquisition.Magnetic resonance in medicine · 2024Article
- Differential functional change in olfactory bulb and olfactory eloquent areas in Parkinson's disease.Brain communications · 2024Article
- Differential Laminar Activation Dissociates Encoding and Retrieval in the Human Medial and Lateral Entorhinal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Evaluation of T2-prepared blood oxygenation level dependent functional magnetic resonance imaging with an event-related task: Hemodynamic response function and reproducibility.Frontiers in neuroscience · 2023Article
- Three-dimensional reduced field-of-view imaging (3D-rFOVI).Magnetic resonance in medicine · 2022Article
- A revisit of the k-space filtering effects of magnetization-prepared 3D FLASH and balanced SSFP acquisitions: Analytical characterization of the point spread functions.Magnetic resonance imaging · 2022Article
- Quantification of cerebral blood volume changes caused by visual stimulation at 3 T using DANTE-prepared dual-echo EPI.Magnetic resonance in medicine · 2022Article
- Impaired response of cerebral oxygen metabolism to visual stimulation in Huntington's disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Functional Activities Detected in the Olfactory Bulb and Associated Olfactory Regions in the Human Brain Using T2-Prepared BOLD Functional MRI at 7T.Frontiers in neuroscience · 2021Article
- Research on BOLD-fMRI Data Denoising Based on Bayesian Estimation and Adaptive Wavelet Threshold.Oxidative medicine and cellular longevity · 2021Article
- A novel spectrally selective fat saturation pulse design with robustness to BMagnetic resonance imaging · 2021Article
- Whole-Brain Functional and Diffusion Tensor MRI in Human Participants with Metallic Orthodontic Braces.Radiology · 2020Article
- The Additional Diagnostic Value of the Three-dimensional Volume Rendering Imaging in Routine Radiology Practice.Cureus · 2019Review
- In vivo magnetic resonance imaging and spectroscopy. Technological advances and opportunities for applications continue to abound.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2019Review
- Techniques for blood volume fMRI with VASO: From low-resolution mapping towards sub-millimeter layer-dependent applications.NeuroImage · 2018Article
- Shuffled magnetization-prepared multicontrast rapid gradient-echo imaging.Magnetic resonance in medicine · 2018Article
- Article
- Language Mapping Using T2-Prepared BOLD Functional MRI in the Presence of Large Susceptibility Artifacts-Initial Results in Patients With Brain Tumor and Epilepsy.Tomography (Ann Arbor, Mich.) · 2017Article
- Memory performance-related dynamic brain connectivity indicates pathological burden and genetic risk for Alzheimer's disease.Alzheimer's research & therapy · 2017Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
purposeA new acquisition scheme for T2-weighted spin-echo BOLD fMRI is introduced.
methodsIt uses a T2-preparation module to induce blood-oxygenation-level-dependent (BOLD) contrast, followed by a single-shot three-dimensional (3D) fast gradient-echo readout with short echo time (TE). It differs from most spin-echo BOLD sequences in that BOLD contrast is generated before the readout, which eliminates the "dead time" due to long TE required for T2 contrast, and substantially improves acquisition efficiency. This approach, termed "3D T2prep-GRE," was implemented at 7 Tesla (T) with a typical spatial (2.5 × 2.5 × 2.5 mm(3) ) and temporal (TR = 2.3 s) resolution for functional MRI (fMRI) and whole-brain coverage (55 slices), and compared with the widely used 2D spin-echo EPI sequence.
resultsIn fMRI experiments of simultaneous visual/motor activities, 3D T2prep-GRE showed minimal distortion and little signal dropout across the whole brain. Its lower power deposition allowed greater spatial coverage (55 versus 17 slices with identical TR, resolution and power level), temporal SNR (60% higher) and CNR (35% higher) efficiency than 2D spin-echo EPI. It also showed smaller T2* contamination.
conclusionThis approach is expected to be useful for ultra-high field fMRI, especially for regions near air cavities. The concept of using T2-preparation to generate BOLD contrast can be combined with many other sequences at any field strength.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.