ReviewHead and neck pathology2014
The sinonasal tract: another potential "hot spot" for carcinomas with transcriptionally-active human papillomavirus.
Review in Head and neck pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 81 citations in OpenAlex.
- EGFR mutations in sinonasal squamous neoplasms: Novel hotspot for exon 20 insertions.Virchows Archiv : an international journal of pathology · 2025Article
- CT scoring system for differentiating of sinonasal inverted papilloma and squamous cell carcinoma arising from inverted papilloma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- HPV11 targeting KDM4A regulates the polarization of macrophage MCell communication and signaling : CCS · 2024Article
- The Potential Role of the Microbiome in the Pathogenesis of Nasal Tumors: A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2024Review
- Rare Head and Neck Cancers and Pathological Diagnosis Challenges: A Comprehensive Literature Review.Diagnostics (Basel, Switzerland) · 2024Review
- Evaluation of high-risk human papillomavirus in sinonasal papillomas and squamous cell carcinomas.Virchows Archiv : an international journal of pathology · 2023Article
- Top 10 Basaloid Neoplasms of the Sinonasal Tract.Head and neck pathology · 2023Review
- Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Nasal Cavity, Paranasal Sinuses and Skull Base.Head and neck pathology · 2022Review
- Molecular Detection Methods in HPV-Related Cancers.Frontiers in oncology · 2022Review
- Sine Qua Non: Sinonasal Inverted Papilloma.Head and neck pathology · 2021Article
- The prognostic significance of human papilloma virus in sinonasal squamous cell carcinoma.Laryngoscope investigative otolaryngology · 2020Article
- Sinonasal Squamous Cell Carcinoma: Etiology, Pathogenesis, and the Role of Human Papilloma Virus.Current otorhinolaryngology reports · 2020Article
- Squamous cell carcinoma associated with inverted papilloma: Recurrence and prognostic factors.Oncology letters · 2020Article
- Prevalence of human papillomavirus in sinonasal squamous cell carcinoma with and without association of inverted papilloma in Eastern China.Infectious agents and cancer · 2020Article
- Human Papillomavirus Related Multiphenotypic Sinonasal Carcinoma: Report of a Case with Early and Progressive Metastatic Disease.Journal of neurological surgery reports · 2019Article
- Association of OX40 gene polymorphisms (rs17568G/A and rs229811A/C) with head and neck squamous cell carcinoma.Molecular biology reports · 2019Article
- Transcriptionally Active High-Risk Human Papillomavirus is Not a Common Etiologic Agent in the Malignant Transformation of Inverted Schneiderian Papillomas.Head and neck pathology · 2017Article
- Sinonasal adenoid cystic carcinoma: Treatment outcomes and association with human papillomavirus.Head & neck · 2017Article
- Prevalence of Human Papilloma Virus in Sinonasal Papilloma in Southern Iranian Population.Journal of dentistry (Shiraz, Iran) · 2017Article
- Virus-associated neoplasms of the nasopharynx and sinonasal tract: diagnostic problems.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2017Review
Corrections and comments
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Authors and funding
13 authors at 11 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While high risk human papillomavirus (HPV) is well established as causative and clinically important for squamous cell carcinoma (SCC) of the oropharynx, its role in non-oropharyngeal head and neck SCC is much less clearly elucidated. In the sinonasal region, in particular, although it is a relatively uncommon site for SCC, as many as 20 % of SCC harbor transcriptionally-active high risk HPV. These tumors almost always have a nonkeratinizing morphology and may have a better prognosis. In addition, specific variants of SCC as well as other rare carcinoma types, when arising in the sinonasal tract, can harbor transcriptionally-active HPV. This article reviews the current literature on HPV in sinonasal carcinomas, attempts to more clearly demonstrate what tumors have it and how this relates to possible precursor lesions like inverted papilloma, and discusses the possible clinical ramifications of the presence of the virus.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.