ArticleEuropean heart journal. Acute cardiovascular care2013
Do clinical factors explain persistent sex disparities in the use of acute reperfusion therapy in STEMI in Sweden and Canada?
Article in European heart journal. Acute cardiovascular care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Doubly blind: a systematic review of gender in randomised controlled trials.Global health action · 2016Pooled it
- The impact of patient sex on intensive care unit admission: a blinded randomized survey.Scientific reports · 2019Trial
- The relation between delayed reperfusion treatment and reduced left ventricular ejection fraction in patients with ST-segment elevation myocardial infarction: a national prospective cohort study.European heart journal open · 2025Article
- Gender Differences in Clinical Practice Regarding Coronary Heart Disease: A Systematic Review.Journal of clinical medicine · 2025Review
- Women's Health Across the Lifespan: A Sex- and Gender-Focused Perspective.Physical therapy · 2024Review
- Article
- Exploring the Impact of Gender Bias Among Medical Trainees.PRiMER (Leawood, Kan.) · 2024Article
- Exploring gender impact on collaborative care planning: insights from a community mental health service study in Italy.BMC psychiatry · 2023Article
- Sex Differences in Acute Coronary Syndromes: A Global Perspective.Journal of cardiovascular development and disease · 2022Review
- Better outcomes from exercise-related out-of-hospital cardiac arrest in males and in the young: findings from the Swedish Registry of Cardiopulmonary Resuscitation.British journal of sports medicine · 2022Article
- Five years of a comprehensive ST-elevation myocardial infarction protocol and its association with sex disparities.European heart journal open · 2021Article
- Age-Related Sex Differences in Clinical Presentation, Management, and Outcomes in ST-Segment-Elevation Myocardial Infarction: Pooled Analysis of 15 532 Patients From 7 Arabian Gulf Registries.Journal of the American Heart Association · 2020Observational
- Aortic Stiffness and Infarct Healing in Survivors of Acute ST-Segment-Elevation Myocardial Infarction.Journal of the American Heart Association · 2020Observational
- Impact of gender on post- traumatic intensive care and outcomes.Scandinavian journal of trauma, resuscitation and emergency medicine · 2019Article
- Cardiac arrest, gender and resuscitation outcomes.Intensive care medicine · 2019Article
- Survival of in-hospital cardiac arrest in men and women in a large Swedish cohort.Scandinavian journal of trauma, resuscitation and emergency medicine · 2018Article
- "Brave Men" and "Emotional Women": A Theory-Guided Literature Review on Gender Bias in Health Care and Gendered Norms towards Patients with Chronic Pain.Pain research & management · 2018Review
- Acute Coronary Syndrome: The Risk to Young Women.Journal of the American Heart Association · 2017Observational
- Sex-based differences in quality of care and outcomes in a health system using a standardized STEMI protocol.American heart journal · 2017Article
- The influence of gender on ICU admittance.Scandinavian journal of trauma, resuscitation and emergency medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThis study examined clinical factors associated with sex differences in the use of acute reperfusion therapy (fibrinolysis or primary percutaneous coronary intervention) in ST-elevation myocardial infarction (STEMI) patients, and the interaction between sex and these factors in Sweden and Canada.
methodsPatients with STEMI in Sweden (n=32,676 from the Register of Information and Knowledge about Swedish Heart Intensive Care Admissions) were compared with similar patients in Canada (n=3375 from the Canadian Global Registry of Acute Coronary Events) for the period 2004-2008.
resultsUnadjusted vs. age-adjusted odds ratios (OR) for no reperfusion (women vs. men) were for Sweden 1.57 (95% CI 1.49-1.64) vs. 1.14 (95% CI 1.08-1.20), and for Canada 1.61 (95% CI 1.39-1.87) vs. OR 1.18 (95% CI 1.01-1.39). Sex differences persisted after multivariable adjustments (including prehospital delay, atypical symptoms, diabetes), factors for which no interaction with sex was found. Among women <60 years, adjusting for atypical symptoms in Canada and angiographic data in Sweden made the greatest contribution to explaining observed sex differences.
conclusionsIn both countries, acute reperfusion therapy in STEMI was used less often in women than in men. Factors associated with these sex differences appear to differ between older and younger women. Targeted interventions are needed to optimize care for women with STEMI, as well as sex- and age-stratified reporting of quality indicators to assess their effectiveness.
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Registered trials
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