Evidence map›Paper›PMID 24337726›Full record

ArticleAIDS and behavior2014

The implications of post-coital intravaginal cleansing for the introduction of vaginal microbicides in South Africa.

Mitzy Gafos, Robert Pool, Misiwe Adelaide Mzimela, Hlengiwe Beauty Ndlovu, Sheena McCormack, Jonathan Elford, MDP team

Abstract read
In one paragraph

Article in AIDS and behavior, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Intravaginal practices among HIV-negative female sex workers along the US-Mexico border and their implications for emerging HIV prevention interventions.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2016
    Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Achieving the optimal vaginal state: using vaginal products and study gels in Uganda, Zimbabwe, and South Africa.International journal of sexual health : official journal of the World Association for Sexual Health · 2017
    Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mitzy GafosAfrica Centre for Health and Population Studies, University of KwaZulu-Natal, Mtubatuba, South Africa, m.gafos@ucl.ac.uk.
Robert Pool
Misiwe Adelaide Mzimela
Hlengiwe Beauty Ndlovu
Sheena McCormack
Jonathan Elford
MDP team

Funding

Medical Research Council G0100137Medical Research Council MC_UU_12023/1Wellcome Trust 082384/Z/07/ZWellcome Trust 097410
6 · The paper itself

Abstract

Post-coital intravaginal cleansing (IVC) could counteract the protective effect of a vaginal microbicide. IVC less than 1 h after sex is discouraged in most microbicide trials. During a microbicide trial in KwaZulu-Natal, we collected quantitative data on post-coital IVC. We discussed IVC during in-depth-interviews (IDIs) and focus-group discussions (FGDs) with women enrolled in the trial, and during FGDs with community members. Nearly one-third (336/1,143) of women reported IVC less than an hour after sex. In multivariate analysis, post-coital IVC was associated with younger age, larger household size, greater sexual activity, consistent gel use, and clinic of enrolment. During IDIs and FGDs, respondents described post-coital IVC as a common hygiene practice motivated by the need to remove semen, vaginal fluids and sweat, although this practice may be amenable to change in the context of microbicide use. We need to consider strategies for influencing post-coital IVC practices in future microbicide trials and delivery programmes.

Indexed as

CoitusAdministration, IntravaginalAdultAnti-Infective AgentsFemaleFocus GroupsHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansHygieneInterviews as TopicMiddle AgedMultivariate AnalysisRural PopulationSexual BehaviorSouth AfricaAnti-Infective Agents

Identifiers

PMID24337726
PMCPMC3905171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.