Evidence map›Paper›PMID 24337725›Full record

Trial reportAIDS and behavior2014

Depressive symptoms and antiretroviral therapy (ART) initiation among HIV-infected Russian drinkers.

Tracie M Goodness, Tibor P Palfai, Debbie M Cheng, Sharon M Coleman, Carly Bridden, Elena Blokhina, Evgeny Krupitsky, Jeffrey H Samet

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS and behavior, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tracie M GoodnessDepartment of Psychology, Boston University, 648 Beacon Street, 4th Floor, Boston, MA, 02215, USA, tgoodnes@bu.edu.
Tibor P Palfai
Debbie M Cheng
Sharon M Coleman
Carly Bridden
Elena Blokhina
Evgeny Krupitsky
Jeffrey H Samet

Funding

URBAN ARCH (2/5) Biostatistics and Data Management Core (BDM)U24AA020779 · NIAAA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CHENG, DEBBIE M. · 2011 to 2020
$3.6M
URBAN ARCH (1/5) Administrative Coordinating Core (Admin Core)U24AA020778 · NIAAA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2011 to 2020
$3.5M
Maximizing Opportunity - HIV Prevention in Hospitalized Russian DrinkersR01AA016059 · NIAAA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2006 to 2010
$3.2M
Impact of Alcohol Use on HIV Infection--In the United States and RussiaK24AA015674 · NIAAA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2006 to 2010
$756k
NIAAA NIH HHS K24 AA015674NIAAA NIH HHS K24AA15674NIAAA NIH HHS R01 AA016059NIAAA NIH HHS R01AA016059NIAAA NIH HHS U24 AA020778NIAAA NIH HHS U24AA020778NIAAA NIH HHS U24 AA020779NIAAA NIH HHS U24AA020779
6 · The paper itself

Abstract

The impact of depressive symptoms on ART initiation among Russian HIV-infected heavy drinkers enrolled in a secondary HIV prevention trial (HERMITAGE) was examined. We assessed 133 participants eligible for ART initiation (i.e., CD4 count <350 cells/μl) who were not on ART at baseline. Depressive symptom severity and ART use were measured at baseline, 6- and 12-months. Association between depressive symptoms and subsequent ART initiation was evaluated using GEE logistic regression adjusting for gender, past ART use, injection drug use and heavy drinking. Depressive symptom severity was not significantly associated with lower odds of initiating ART. Cognitive depression symptoms were not statistically significant (global p = 0.05); however, those with the highest level of severity had an AOR of 0.25 (95 % CI 0.09-0.71) for delayed ART initiation. Although the effect of depression severity was not significant, findings suggest a potential role of cognitive depression symptoms in decisions to initiate ART in this population.

Indexed as

AdultAlcohol DrinkingAnti-HIV AgentsCD4 Lymphocyte CountDepressionDrug MonitoringFemaleFollow-Up StudiesHIV InfectionsHumansLogistic ModelsMaleMedication AdherenceRussiaSubstance Abuse, IntravenousSurveys and QuestionnairesAnti-HIV Agents

Identifiers

PMID24337725
PMCPMC4020947

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.