ArticleClinical rheumatology2015
Interrelationships between pain processing, cortisol and cognitive performance in chronic whiplash-associated disorders.
Article in Clinical rheumatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Evidence for Cognitive Decline in Chronic Pain: A Systematic Review and Meta-Analysis.Frontiers in neuroscience · 2021Pooled it
- The Relationship Between Chronic Pain and Neurocognitive Function: A Systematic Review.The Clinical journal of pain · 2018Pooled it
- Cognitive impairment and pain in depression: The mediating role of the kynurenine pathway.World journal of psychiatry · 2025Article
- Measuring resilience to chronic pain in population surveys using hair cortisol.Psychological medicine · 2025Article
- The Role of Serotonergic and Noradrenergic Descending Pathways on Performance-Based Cognitive Functioning at Rest and in Response to Exercise in People with Chronic Whiplash-Associated Disorders: A Randomized Controlled Crossover Study.Clinics and practice · 2023Article
- [Cognition and driving ability in chronic pain syndrome].Der Nervenarzt · 2023Review
- Association between Experimental Pain Measurements and the Central Sensitization Inventory in Patients at Least 3 Months after COVID-19 Infection: A Cross-Sectional Pilot Study.Journal of clinical medicine · 2023Article
- Persistent inflammatory pain is linked with anxiety-like behaviors, increased blood corticosterone, and reduced global DNA methylation in the rat amygdala.Molecular pain · 2022Article
- Better Executive Functions Are Associated With More Efficient Cognitive Pain Modulation in Older Adults: An fMRI Study.Frontiers in aging neuroscience · 2022Article
- Emotional affection on a sustained attention task: The importance the aging process and depression.PloS one · 2020Article
- The interaction between stress and chronic pain through the lens of threat learning.Neuroscience and biobehavioral reviews · 2019Review
- Differences in white matter structure and cortical thickness between patients with traumatic and idiopathic chronic neck pain: Associations with cognition and pain modulation?Human brain mapping · 2018Article
- Chronic Pain and Chronic Stress: Two Sides of the Same Coin?Chronic stress (Thousand Oaks, Calif.) · 2017Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study aims at studying interactions between cognitive performance and conditioned pain modulation in patients with chronic whiplash-associated disorders (WAD) and healthy controls. In addition, the relation between cortisol concentrations and cognitive performance will be studied in patients with chronic WAD. Thirty-one subjects, 16 healthy subjects and 15 patients with chronic WAD, were enrolled and subjected to several self-report and physiological measures. Self-report measures encompassed pain rating during a procedure evaluating conditioned pain modulation. Afterward, they were subjected to physiological measures, which are cognitive tests (Stroop task, psychomotor vigilance task, and operation span task) preceded and followed by salivary cortisol concentration measurements. Chronic WAD patients performed worse in recall at the operation span task and presented longer reaction times at the psychomotor vigilance task and at the Stroop task when sleep-related words were shown (p < .05). Conditioned pain modulation and cortisol concentrations were not significantly different between patients and controls (p > .05). Only in the healthy subjects, conditioned pain modulation and baseline cortisol concentrations were correlated to cognitive performance (p < .05). This is the first study addressing the relation between pain inhibition and cognitive performance in chronic WAD. We did not reveal impaired pain inhibition but did reveal cognitive dysfunctions in patients with chronic WAD. In healthy subjects, pain inhibition was related to cognitive performance but not in the patient group.
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