Evidence map›Paper›PMID 24337665›Full record

ArticleJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2014

Preoperative beta-blocker treatment is a key for deciding left ventricular assist device implantation strategy as a bridge to recovery.

Teruhiko Imamura, Koichiro Kinugawa, Masaru Hatano, Takeo Fujino, Hironori Muraoka, Toshiro Inaba, Hisataka Maki, Yukie Kagami, Miyoko Endo, Osamu Kinoshita and 3 more

Abstract read
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In one paragraph

Article in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Benefits of Neurohormonal Therapy in Patients With Continuous-Flow Left Ventricular Assist Devices.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2020
    Article
  5. A case of cardiogenic shock due to acute coronary syndrome successfully recovered by percutaneous and paracorporeal left ventricular assist device.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2019
    Article
  6. Single-center experience of the bridge-to-bridge strategy using the Nipro paracorporeal ventricular assist device.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2018
    Article
  7. Article
  8. Article
  9. Journal of Artificial Organs 2014: the year in review.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2015
    Article
  10. Current status of extracorporeal ventricular assist devices in Japan.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Teruhiko ImamuraDepartment of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan, imamurate-int@h.u-tokyo.ac.jp.
Koichiro Kinugawa
Masaru Hatano
Takeo Fujino
Hironori Muraoka
Toshiro Inaba
Hisataka Maki
Yukie Kagami
Miyoko Endo
Osamu Kinoshita
Kan Nawata
Shunei Kyo
Minoru Ono

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To date, there have been few reports demonstrating preoperative predictors for left ventricular reverse remodeling (LVRR) after LV assist device (LVAD) implantation, especially among patients with dilated cardiomyopathy (DCM). We retrospectively analyzed 60 patients with stage D heart failure due to DCM who had received LVAD treatment [pulsatile flow (PF) type, 26; continuous flow type, 34]. Data were evaluated at 6 months or just before explantation of the LVAD. We defined "LV reverse remodeling" (LVRR) by the achievement of an LV ejection fraction (LVEF) of ≥ 35 % after 6 months of LVAD support or explantation of LVAD within 6 months. LVRR occurred in 16 of our patients (26.7 %). Uni/multivariate logistic regression analyses for LVRR demonstrated that of the preoperative variables evaluated, PF LVAD usage and insufficient preoperative β-blocker treatment were independent predictors for LVRR. Patients who accomplished LVRR had a better clinical course, including lower levels of aortic valve insufficiency and lower levels of plasma B-type natriuretic peptide. Of the six patients (10.0 %) in whom LVADs were eventually explanted, all had an LVEF of ≥ 35 % before explantation or at 6 months. Based on these results, we conclude that DCM patients with insufficient preoperative β-blocker treatment have a chance to achieve LVRR under LVAD support as a bridge to recovery.

Indexed as

Heart-Assist DevicesVentricular RemodelingAdrenergic beta-AntagonistsAdultCardiomyopathy, DilatedFemaleHeart FailureHumansMaleMiddle AgedMultivariate AnalysisPulsatile FlowRetrospective StudiesYoung AdultAdrenergic beta-Antagonists

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.