ArticlePsychiatric services (Washington, D.C.)2014
Changes in physician antipsychotic prescribing preferences, 2002-2007.
Article in Psychiatric services (Washington, D.C.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Development of the treatment prediction model in the artificial intelligence in depression - medication enhancement study.Npj mental health research · 2025Article
- The definition and measurement of heterogeneity.Translational psychiatry · 2020Review
- Oral antipsychotic prescribing and association with neighbourhood-level socioeconomic status: analysis of time trend of routine primary care data in England, 2011-2016.Social psychiatry and psychiatric epidemiology · 2020Article
- We need an operational framework for heterogeneity in psychiatric researchJournal of psychiatry & neuroscience : JPN · 2020Article
- Association between physician adoption of a new oral anti-diabetic medication and Medicare and Medicaid drug spending.BMC health services research · 2019Article
- Can Academic Detailing Move the Needle for Patients with Diabetes in a State-Based Prescription Drug Benefit Program?American health & drug benefits · 2019Article
- Use of Academic Detailing With Audit and Feedback to Improve Antipsychotic Pharmacotherapy.Psychiatric services (Washington, D.C.) · 2018Article
- Risk of weight gain for specific antipsychotic drugs: a meta-analysis.NPJ schizophrenia · 2018Article
- Gaps in Psychiatric Training Could Challenge Delivery of Optimal Schizophrenia Pharmacotherapy.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2018Article
- Psychotropic Drug-Related Fall Incidents in Nursing Home Residents Living in the Eastern Part of The Netherlands.Drugs in R&D · 2017Article
- A Retrospective Cohort Study of Acute Kidney Injury Risk Associated with Antipsychotics.CNS drugs · 2017Article
- Antipsychotic Use Pattern in Schizophrenia Outpatients: Correlates of Polypharmacy.Clinical practice and epidemiology in mental health : CP & EMH · 2017Article
- Who Were the Early Adopters of Dabigatran?: An Application of Group-based Trajectory Models.Medical care · 2016Article
- Patient, Physician and Organizational Influences on Variation in Antipsychotic Prescribing Behavior.The journal of mental health policy and economics · 2016Article
- Article
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Authors and funding
6 authors.
Funding
Abstract
objectivePhysician antipsychotic prescribing behavior may be influenced by comparative effectiveness evidence, regulatory warnings, and formulary and other restrictions on these drugs. This study measured changes in the degree to which physicians are able to customize treatment choices and changes in physician preferences for specific agents after these events.
methodsThe study used 2002-2007 prescribing data from the IMS Health Xponent database and data on physician characteristics from the American Medical Association for a longitudinal cohort of 7,399 physicians. Descriptive and multivariable regression analyses were conducted of the concentration of prescribing (physician-level Herfindahl index) and preferences for and likelihood of prescribing two first-generation antipsychotics and six second-generation antipsychotics. Analyses adjusted for prescribing volume, specialty, demographic characteristics, practice setting, and education.
resultsAntipsychotic prescribing was highly concentrated at the physician level, with a mean unadjusted Herfindahl index of .33 in 2002 and .29 in 2007. Psychiatrists reduced the concentration of their prescribing more over time than did other physicians. High-volume psychiatrists had a Herfindahl index that was half that of low-volume physicians in other specialties (.18 versus .36), a difference that remained significant (p<.001) after adjustment for physician characteristics. The share of physicians preferring olanzapine dropped from 29.9% in 2002 to 10.3% in 2007 (p<.001) while the share favoring quetiapine increased from 9.4% to 44.5% (p<.001). Few physicians (<5%) preferred a first-generation antipsychotic in 2002 or 2007.
conclusionsPreferences for specific antipsychotics changed dramatically during this period. Although physician prescribing remained heavily concentrated, the concentration decreased over time, particularly among psychiatrists.
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