Evidence map›Paper›PMID 24336800›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2014

Lower extremity function trajectories in the African American Health Cohort.

Fredric D Wolinsky, Padmaja Ayyagari, Theodore K Malmstrom, J Phillip Miller, Elena M Andresen, Mario Schootman, Douglas K Miller

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Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Fredric D WolinskyDepartment of Health Management and Policy, College of Public Health, The University of Iowa. fredric-wolinsky@uiowa.edu.
Padmaja AyyagariDepartment of Health Management and Policy, College of Public Health, The University of Iowa.
Theodore K MalmstromDepartment of Neurology & Psychiatry, School of Medicine, Saint Louis University, Missouri.
J Phillip MillerDepartment of Biostatistics, Washington University in St. Louis, Missouri.
Elena M AndresenDepartment of Public Health and Preventive Medicine, Oregon Health & Science University, Portland.
Mario SchootmanDepartment of Epidemiology, School of Public Health, Saint Louis University, Missouri.
Douglas K MillerCenter for Aging Research, Indiana University & the Regenstrief Institute, Indianapolis.

Funding

PHYSICAL FRAILTY IN URBAN AFRICAN-AMERICANSR01AG010436 · NIA · SAINT LOUIS UNIVERSITY · PI DAVILA-ROMAN, VICTOR G. · 1991 to 2011
$8.5M
NIA NIH HHS AG 010436
6 · The paper itself

Abstract

backgroundWe addressed two understudied issues in estimating lower extremity functional trajectories in older adults-incorporating the effect of mortality and evaluating heterogeneity among African Americans.

methodsData were taken from the 998 participants in the African American Health cohort. A highly reliable and valid 8-item lower extremity function scale was used at baseline and at the 1-, 2-, 3-, 4-, 7-, and 9-year follow-up interviews. Semiparametric (ie, discrete) group-based mixture modeling identified the trajectories, and multinomial logistic regression identified risk factors for differential trajectory groups.

resultsWhen treating mortality as informative censoring, six discrete trajectories were observed with 45% of the participants belonging to three stable trajectories (good, fair, or poor function), and the remainder belonging to three declining trajectories (very high function with minimal improvement then minimal decline, very good function with a slow and modest decline, and very good function with a large and quick decline).

conclusionSubstantial heterogeneity in lower extremity function trajectories exists in the African American Health cohort, after appropriately treating mortality as informative censoring.

Indexed as

Black or African AmericanGeriatric AssessmentHealth StatusAgedAgingComorbidityFactor Analysis, StatisticalFemaleHumansLife StyleLogistic ModelsLower ExtremityMaleMiddle AgedMortalityPsychometricsDisablement processEpidemiology.Functional performanceMinority aging

Identifiers

PMID24336800
PMCPMC4158401

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.