ArticleReproductive sciences (Thousand Oaks, Calif.)2014
Mmu-miR-193 is involved in embryo implantation in mouse uterus by regulating GRB7 gene expression.
Article in Reproductive sciences (Thousand Oaks, Calif.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Plasticizer DEHP exposure in early pregnancy affects the endometrial decidualization in mice through reducing lncRNAZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2023Article
- MicroRNAs in the Regulation of Endometrial Receptivity for Embryo Implantation.International journal of molecular sciences · 2022Review
- Impairment of endometrial decidual reaction in early pregnant mice fed with high fat diet.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2022Article
- Role of endometrial microRNAs in repeated implantation failure (mini-review).Frontiers in cell and developmental biology · 2022Review
- Article
- Transcriptomic analysis and competing endogenous RNA network in the human endometrium between proliferative and mid-secretory phases.Experimental and therapeutic medicine · 2021Article
- miR-21a inhibits decidual cell apoptosis by targeting Pdcd4.Genes & diseases · 2021Article
- The Role of MicroRNAs in Mammalian Fertility: From Gametogenesis to Embryo Implantation.International journal of molecular sciences · 2020Review
- Genome-wide analysis and functional prediction of long non-coding RNAs in mouse uterus during the implantation window.Oncotarget · 2017Article
- MicroRNA-181a is involved in the regulation of human endometrial stromal cell decidualization by inhibiting Krüppel-like factor 12.Reproductive biology and endocrinology : RB&E · 2015Article
- Let-7-mediated suppression of mucin 1 expression in the mouse uterus during embryo implantation.The Journal of reproduction and development · 2015Article
- Analysis of miRNA Expression in Bovine Endometrium During the Estrous Cycle.Animal science journal = Nihon chikusan GakkaihoArticle
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Embryo implantation is a complicated process involving a series of endometrial changes that depend on differential gene expression. MicroRNAs (miRNAs) are important for regulation of gene expression. Previous studies have shown that miRNAs may participate in the regulation of gene expression during embryo implantation. To explore the role of endometrial miRNAs in early murine pregnancy, we used microarrays to investigate whether miRNAs were differentially expressed in the mouse endometrium on pregnancy day 4 (D4) and day 6 (D6). The results demonstrated that 17 miRNAs were upregulated and 18 were downregulated (>2-fold) in D6 endometria compared to D4. We identified that mmu-miR-193 exhibited the highest upregulation on D6, and the upregulation of mmu-miR-193 before embryo implantation could reduce the embryo implantation rate. Further, we demonstrated that mmu-miR-193 influenced embryo implantation by regulating growth factor receptor-bound protein 7 expression. In summary, our study suggests that mmu-miR-193 plays an important role in embryo implantation.
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