Evidence map›Paper›PMID 24336185›Full record

ReviewNature reviews. Microbiology2014

Bacterial programmed cell death: making sense of a paradox.

Kenneth W Bayles

Abstract readReview
In one paragraph

Review in Nature reviews. Microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

124 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Temperate phages limit their own propagation under spatial constraint in biofilms on chitin.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Interaction BetweenMicroorganisms · 2025
    Article
  11. Article
  12. Flow cytometry study ofFrontiers in microbiology · 2025
    Article
  13. Article
  14. Article
  15. Unravelling the key steps impairing the metabolic state of Xanthomonas cells undergoing programmed cell death.International microbiology : the official journal of the Spanish Society for Microbiology · 2024
    Article
  16. Article
  17. Article
  18. Novel endolithic bacteria of phylumApplied and environmental microbiology · 2024
    Article
  19. Review
  20. Article

64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Kenneth W BaylesCenter for Staphylococcal Research, Department of Pathology & Microbiology, The University of Nebraska Medical Center, Omaha, Nebraska 68198, USA.

Funding

The S. aureus biofilm lifecycleP01AI083211 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BAYLES, KENNETH W. · 2009 to 2023
$32.1M
The molecular control of bacterial autolysisR01AI038901 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BAYLES, KENNETH W. · 2003 to 2012
$3.1M
NOVEL S AUREUS LOCUS THAT AFFECTS AUTOLYSISR29AI038901 · NIAID · UNIVERSITY OF IDAHO · PI BAYLES, KENNETH W. · 1997 to 2001
$182k
NIAID NIH HHS P01 AI083211NIAID NIH HHS P01‑AI83211NIAID NIH HHS R01 AI038901NIAID NIH HHS R01‑AI038901
6 · The paper itself

Abstract

Although the concept of programmed cell death (PCD) in bacteria has been met with scepticism, a growing body of evidence suggests that it can no longer be ignored. Several recent studies indicate that the phenotypic manifestations of apoptosis, which are processes that are associated with ordered cellular disassembly in eukaryotes, are conserved in bacteria. In this Opinion article, I propose a model for the coordinated control of potential bacterial PCD effectors and argue that the processes involved are functionally analogous to eukaryotic PCD systems.

Indexed as

BacteriaBacterial ProteinsCell DeathDNA DamageEukaryotaModels, BiologicalPhenotypeBacterial Proteins

Identifiers

PMID24336185
PMCPMC4422510

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.