Evidence map›Paper›PMID 24336026›Full record

ArticleInternational journal of environmental research and public health2013

Maternal exposure to bisphenol-A and fetal growth restriction: a case-referent study.

Igor Burstyn, Jonathan W Martin, Sanjay Beesoon, Fiona Bamforth, Qiaozhi Li, Yutaka Yasui, Nicola M Cherry

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Neuro-toxic and Reproductive Effects of BPA.Current neuropharmacology · 2019
    Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Igor BurstynDivision of Preventive Medicine, Department of Medicine, Faculty of Medicine and Dentistry, The University of Alberta, Edmonton, AB T6G 2G3, Canada. igor.burstyn@drexel.edu.
Jonathan W Martin
Sanjay Beesoon
Fiona Bamforth
Qiaozhi Li
Yutaka Yasui
Nicola M Cherry
University of Alberta · CA

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

We conducted a case-referent study of the effect of exposure to bisphenol-A on fetal growth in utero in full-term, live-born singletons in Alberta, Canada. Newborns <10 percentile of expected weight for gestational age and sex were individually matched on sex, maternal smoking and maternal age to referents with weight appropriate to gestational age. Exposure of the fetus to bisphenol-A was estimated from maternal serum collected at 15-16 weeks of gestation. We pooled sera across subjects for exposure assessment, stratified on case-referent status and sex. Individual 1:1 matching was maintained in assembling 69 case and 69 referent pools created from 550 case-referent pairs. Matched pools had an equal number of aliquots from individual women. We used an analytical strategy conditioning on matched set and total pool-level values of covariates to estimate individual-level effects. Pools of cases and referents had identical geometric mean bisphenol-A concentrations (0.5 ng/mL) and similar geometric standard deviations (2.3-2.5). Mean difference in concentration between matched pools was 0 ng/mL, standard deviation: 1 ng/mL. Stratification by sex and control for confounding did not suggest bisphenol-A increased fetal growth restriction. Our analysis does not provide evidence to support the hypothesis that bisphenol-A contributes to fetal growth restriction in full-term singletons.

Indexed as

Environmental ExposureMaternal ExposureAdultAlbertaBenzhydryl CompoundsBisphenol A CompoundsCase-Control StudiesEndocrine DisruptorsEnvironmental MonitoringEnvironmental PollutantsFemaleFetal BloodFetal Growth RetardationGrowth and DevelopmentHumansInfant, NewbornBenzhydryl Compoundsbisphenol ABisphenol A CompoundsEndocrine DisruptorsEnvironmental PollutantsPhenols

Identifiers

PMID24336026
PMCPMC3881152
OpenAlexW1969243040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.