ArticleProceedings. Biological sciences2014
Evolutionary inevitability of sexual antagonism.
Article in Proceedings. Biological sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.
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Who cites it
62 citing papers in PubMed, 2 syntheses or guidelines pooled it, 163 citations in OpenAlex.
- Systematic review reveals multiple sexually antagonistic polymorphisms affecting human disease and complex traits.Evolution; international journal of organic evolution · 2021Pooled it
- Climatic factors and species range position predict sexually antagonistic selection across taxa.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Pooled it
- Sublethal Clothianidin Exposure Increases Trait Variation and Drives Sex-Specific Selection in the Water StriderEcology and evolution · 2026Article
- Sexual antagonism, mating systems, and recombination suppression on sex chromosomes.Evolution letters · 2026Article
- Integrated methylome and transcriptome analysis provides insight into DNA methylation-mediated networks in sexual dimorphism of Vernicia montana.BMC plant biology · 2026Article
- The relationship between sexual dimorphism and intersex correlation: do models support intuition?Genetics · 2025Article
- Pervasive sex-dependent effects in the genetic architecture of starvation resistance inScience advances · 2025Article
- Effects of inbreeding on balancing selection: insights from Fisher's geometric model.Genetics · 2025Article
- The maintenance of genetic polymorphism underlying sexually antagonistic traits.Evolution letters · 2025Article
- Reconciling theories of dominance with the relative rates of adaptive substitution on sex chromosomes and autosomes.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Dominance reversals: the resolution of genetic conflict and maintenance of genetic variation.Proceedings. Biological sciences · 2024Review
- Mother's Curse effects on lifespan and aging.Frontiers in aging · 2024Review
- The roles of sexual selection and sexual conflict in shaping patterns of genome and transcriptome variation.Nature ecology & evolution · 2023Review
- Carry-over effects and fitness trade-offs in marine life histories: The costs of complexity for adaptation.Evolutionary applications · 2023Article
- Systematic review reveals sexually antagonistic knockouts in model organisms.Ecology and evolution · 2022Review
- Differing associations between sex determination and sex-linked inversions in two ecotypes ofEvolution letters · 2022Article
- Article
- Why not Y naught.Heredity · 2022Review
- The relationship between sexual dimorphism and androgen response element proliferation in primate genomes.Evolution; international journal of organic evolution · 2022Article
- The Evolution of Widespread Recombination Suppression on the Dwarf Hamster (Phodopus) X Chromosome.Genome biology and evolution · 2022Article
2 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Sexual antagonism, whereby mutations are favourable in one sex and disfavourable in the other, is common in natural populations, yet the root causes of sexual antagonism are rarely considered in evolutionary theories of adaptation. Here, we explore the evolutionary consequences of sex-differential selection and genotype-by-sex interactions for adaptation in species with separate sexes. We show that sexual antagonism emerges naturally from sex differences in the direction of selection on phenotypes expressed by both sexes or from sex-by-genotype interactions affecting the expression of such phenotypes. Moreover, modest sex differences in selection or genotype-by-sex effects profoundly influence the long-term evolutionary trajectories of populations with separate sexes, as these conditions trigger the evolution of strong sexual antagonism as a by-product of adaptively driven evolutionary change. The theory demonstrates that sexual antagonism is an inescapable by-product of adaptation in species with separate sexes, whether or not selection favours evolutionary divergence between males and females.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.