ReviewVirulence2014
Severe sepsis and septic shock: management and performance improvement.
Review in Virulence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07172451 (Efficacy and Safety of Balanced Gelatin Solution for Fluid Infusion in Sepsis Patients Undergoing Emergency Abdominal Surgery), which is not on this map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy and Safety of Balanced Gelatin Solution for Fluid Infusion in Sepsis Patients Undergoing Emergency Abdominal Surgery: A Multicenter, Adaptive Designed, Randomized Controlled Trial
Who cites it
30 citing papers in PubMed, 80 citations in OpenAlex.
- [Efficacy and safety of early physical therapy for acute gastrointestinal injury during mechanical ventilation in patients with sepsis: a randomized controlled pilot trial].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2019Trial
- Efficacy and Safety of a Balanced Gelatine Solution for Fluid Resuscitation in Sepsis: A Prospective, Randomised, Controlled, Double-Blind Trial-GENIUS Trial.Journal of clinical medicine · 2025Article
- Systemic Inflammatory Response Syndrome, Thromboinflammation, and Septic Shock in Fetuses and Neonates.International journal of molecular sciences · 2025Review
- The chain of survival and rehabilitation for sepsis: concepts and proposals for healthcare trajectory optimization.Annals of intensive care · 2024Review
- Phosphorylation-mediated PI3K-Art signalling pathway as a therapeutic mechanism in the hydrogen-induced alleviation of brain injury in septic mice.Journal of cellular and molecular medicine · 2022Article
- The Surviving Sepsis Campaign: research priorities for the administration, epidemiology, scoring and identification of sepsis.Intensive care medicine experimental · 2021Review
- Article
- An evaluation of suspected cases of Hantavirus infection admitted to a tertiary care university hospital in Düzce, Turkey, between 2012 and 2018Turkish journal of medical sciences · 2021Article
- Article
- Capsaicin protects cardiomyocytes against lipopolysaccharide-induced damage via 14-3-3γ-mediated autophagy augmentation.Frontiers in pharmacology · 2021Article
- The Diagnostic and Prognostic Role of Vascular Endothelial Growth Factor C in Sepsis and Septic Shock.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2020Article
- iTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment.Drug design, development and therapy · 2020Article
- Toddalolactone Protects Lipopolysaccharide-Induced Sepsis and Attenuates Lipopolysaccharide-Induced Inflammatory Response by Modulating HMGB1-NF-κB Translocation.Frontiers in pharmacology · 2020Article
- DNA methylation of a NF-κB binding site in the aquaporin 5 promoter impacts on mortality in sepsis.Scientific reports · 2019Article
- Effects of a multifaceted intervention QI program to improve ICU performance.BMC health services research · 2018Article
- Function of aquaporins in sepsis: a systematic review.Cell & bioscience · 2018Review
- Retinal arterial blood flow and retinal changes in patients with sepsis: preliminary study using fluorescein angiography.Critical care (London, England) · 2017Observational
- AQP5-1364A/C polymorphism and the AQP5 expression influence sepsis survival and immune cell migration: a prospective laboratory and patient study.Journal of translational medicine · 2016Article
- Impact of treatment with biologic DMARDs on the risk of sepsis or mortality after serious infection in patients with rheumatoid arthritis.Annals of the rheumatic diseases · 2016Observational
- Diagnosing sepsis - The role of laboratory medicine.Clinica chimica acta; international journal of clinical chemistry · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Morbidity and mortality from sepsis remains unacceptably high. Large variability in clinical practice, plus the increasing awareness that certain processes of care associated with improved critical care outcomes, has led to the development of clinical practice guidelines in a variety of areas related to infection and sepsis. The Surviving Sepsis Guidelines for Management of Severe Sepsis and Septic Shock were first published in 2004, revised in 2008, and recently revised again and published in 2013. The first part of this manuscript is a summary of the 2013 guidelines with some editorial comment. The second part of the manuscript characterizes hospital based sepsis performance improvement programs and highlights the sepsis bundles from the Surviving Sepsis Campaign as a key component of such a program.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.