Evidence map›Paper›PMID 24335433›Full record

ReviewBioengineered

Biologically inspired intelligent decision making: a commentary on the use of artificial neural networks in bioinformatics.

Timmy Manning, Roy D Sleator, Paul Walsh

Abstract readReview
In one paragraph

Review in Bioengineered. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  20. Predicting outcomes in patients with perforated gastroduodenal ulcers: artificial neural network modelling indicates a highly complex disease.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2015
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Timmy ManningDepartment of Computer Science; Cork Institute of Technology; Cork, Ireland.
Roy D SleatorDepartment of Biological Sciences; Cork Institute of Technology; Cork, Ireland.
Paul WalshNSilico Ltd; Rubicon Innovation Centre; Cork, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial neural networks (ANNs) are a class of powerful machine learning models for classification and function approximation which have analogs in nature. An ANN learns to map stimuli to responses through repeated evaluation of exemplars of the mapping. This learning approach results in networks which are recognized for their noise tolerance and ability to generalize meaningful responses for novel stimuli. It is these properties of ANNs which make them appealing for applications to bioinformatics problems where interpretation of data may not always be obvious, and where the domain knowledge required for deductive techniques is incomplete or can cause a combinatorial explosion of rules. In this paper, we provide an introduction to artificial neural network theory and review some interesting recent applications to bioinformatics problems.

Indexed as

AlgorithmsDecision Support TechniquesAnimalsBiomimeticsComputational BiologyDecision MakingDecision Making, Computer-AssistedHumansNerve NetNeural Networks, ComputerPattern Recognition, Automatedartificial neural networksbioinformaticsgene-gene interactiongene identificationgenome wide association studymultilayer perceptronprotein structure prediction

Identifiers

PMID24335433
PMCPMC4049912

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.