ArticleVeterinary pathology2014
Mycobacterium microti tuberculosis in its maintenance host, the field vole (Microtus agrestis): characterization of the disease and possible routes of transmission.
Article in Veterinary pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- Tuberculosis in wild animals in India.Veterinary research communications · 2024Review
- Eco-epidemiological screening of multi-host wild rodent communities in the UK reveals pathogen strains of zoonotic interest.International journal for parasitology. Parasites and wildlife · 2022Article
- ExperimentalMicroorganisms · 2022Article
- Tuberculosis in badgers where the bovine tuberculosis epidemic is expanding in cattle in England.Scientific reports · 2021Article
- Article
- Interaction Patterns between Wildlife and Cattle Reveal Opportunities for Mycobacteria Transmission in Farms from North-Eastern Atlantic Iberian Peninsula.Animals : an open access journal from MDPI · 2021Article
- Mycobacterium microti Infections in Free-Ranging Red Deer (Cervus elaphus).Emerging infectious diseases · 2021Review
- Article
- Pathogenomic analyses ofMicrobial genomics · 2021Article
- Detection of Wood Mice (Microorganisms · 2020Article
- Article
- Comparing the Metabolic Capabilities of Bacteria in theMicroorganisms · 2019Review
- A New Phylogenetic Framework for the Animal-AdaptedFrontiers in microbiology · 2018Article
- Host-parasite biology in the real world: the field voles of Kielder.Parasitology · 2014Review
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
Abstract
The field vole (Microtus agrestis) is a known maintenance host of Mycobacterium microti. Previous studies have shown that infected animals develop tuberculosis. However, the disease is also known in cats and is sporadically reported from humans and other mammalian species. We examined trapped field voles from an endemic area, using a range of diagnostic approaches. These confirmed that a combination of gross and histological examination with culture is most appropriate to identify the true prevalence of the disease, which was shown to be more than 13% at times when older animals that have previously been shown to be more likely to develop the disease dominate the population. The thorough pathological examination of diseased animals showed that voles generally develop systemic disease with most frequent involvement of spleen and liver, followed by skin, lymph nodes, and lungs. The morphology of the lesions was consistent with active disease, and their distribution suggested skin wounds or oral and/or aerogenic infection as the main portal of entry. The demonstration of mycobacteria in open skin lesions, airways, and salivary glands indicated bacterial shedding from the skin and with sputum and saliva. This suggests not only the environment but also direct contact and devouring as likely sources of infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.