ArticleNeurotoxicology and teratology
Adolescent risk-taking as a function of prenatal cocaine exposure and biological sex.
Article in Neurotoxicology and teratology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic Review: Polysubstance Prevalence Estimates Reported during Pregnancy, US, 2009-2020.Maternal and child health journal · 2023Pooled it
- Oscillatory Dynamics of Feedback Processing in Adolescents with Prenatal Cocaine Exposure.Developmental neuropsychology · 2019Article
- Sex differences in neural mechanisms mediating reward and addiction.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019Review
- Doubling down: increased risk-taking behavior following a loss by individuals with cocaine use disorder is associated with striatal and anterior cingulate dysfunction.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2017Article
- Cocaine-induced neurodevelopmental deficits and underlying mechanisms.Birth defects research. Part C, Embryo today : reviews · 2016Review
- Gender-related Differences in Inhibitory Control and Sustained Attention among Adolescents with Prenatal Cocaine Exposure.The Yale journal of biology and medicine · 2016Article
- Reversal Learning Deficits Associated with Increased Frontal Cortical Brain-Derived Neurotrophic Factor Tyrosine Kinase B Signaling in a Prenatal Cocaine Exposure Mouse Model.Developmental neuroscience · 2016Article
- Prenatal cocaine exposure and age of sexual initiation: direct and indirect effects.Drug and alcohol dependence · 2014Article
- Effects of prenatal cocaine exposure on adolescent development.Neurotoxicology and teratologyArticle
- Prenatal drug exposure and executive function in early adolescence.Neurotoxicology and teratologyArticle
- Prenatal cocaine exposure, early cannabis use, and risky sexual behavior at age 25.Neurotoxicology and teratologyArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveTo examine the effects of prenatal cocaine exposure and biological sex on adolescent risk-taking while controlling for early environmental risk.
methodsAdolescents (n=114, mean age=16) were grouped according to high and low risk-taking propensity as measured by the Balloon Analogue Risk Task (BART). Prenatal cocaine exposure was assessed at birth, while environmental risk was assessed at three points during early childhood.
resultsA binary regression analysis indicated that males were 3.5 times more likely than females to be high risk-takers. Biological sex and prenatal cocaine exposure interacted such that exposed males were most likely to be high risk-takers while exposed females were the least likely to be high risk-takers. This pattern held after controlling for prenatal alcohol exposure and early environmental risk. Early environmental risk did not predict adolescent risk-taking.
conclusionsThese findings complement and extend earlier research demonstrating that prenatal cocaine exposure interacts with biological sex in domains related to inhibitory control, emotion regulation, antisocial behavior, and health risk behaviors during preadolescence.
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