ArticleNeuroscience letters2014
Shortened cortical silent period in adductor spasmodic dysphonia: evidence for widespread cortical excitability.
Article in Neuroscience letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02565407 (Robot-aided Proprioceptive Rehabilitation Training With Additional Vibro-tactile Feedback), which is not on this map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Robot-aided Proprioceptive Rehabilitation Training With Additional Vibro-tactile Feedback
Who cites it
23 citing papers in PubMed, 40 citations in OpenAlex.
- Thalamic Deep Brain Stimulation for Spasmodic Dysphonia: A Phase I Prospective Randomized Double-Blind Crossover Trial.Neurosurgery · 2021Trial
- "Tapping" into neural inhibition in focal hand dystonia: an evaluation of a finger-tapping task using TMS and fMRI.Journal of neurology · 2026Article
- Laryngeal Vibration to Treat Abductor-Type Laryngeal Dystonia: Effectiveness and Cortical Response.The Laryngoscope · 2026Article
- Spasmodic Dysphonia.World journal of otorhinolaryngology - head and neck surgery · 2025Review
- Exploring Neurophysiological Mechanisms and Treatment Efficacies in Laryngeal Dystonia: A Transcranial Magnetic Stimulation Approach.Brain sciences · 2023Review
- Probing the inhibitory motor circuits in adductor laryngeal dystonia during a dystonia-unrelated task.Parkinsonism & related disorders · 2023Article
- Effects of low-frequency repetitive transcranial magnetic stimulation in adductor laryngeal dystonia: a safety, feasibility, and pilot study.Experimental brain research · 2022Article
- Temporal specificity of abnormal neural oscillations during phonatory events in laryngeal dystonia.Brain communications · 2022Article
- The effects of continuous oromotor activity on speech motor learning: speech biomechanics and neurophysiologic correlates.Experimental brain research · 2021Article
- Laryngeal Dystonia: Multidisciplinary Update on Terminology, Pathophysiology, and Research Priorities.Neurology · 2021Review
- Contemporary clinical neurophysiology applications in dystonia.Journal of neural transmission (Vienna, Austria : 1996) · 2021Review
- Hyperactive sensorimotor cortex during voice perception in spasmodic dysphonia.Scientific reports · 2020Article
- Evidence for normal intracortical inhibitory recruitment properties in cervical dystonia.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2020Article
- Reduced Interhemispheric Coherence in Cerebellar Kainic Acid-Induced Lateralized Dystonia.Frontiers in neurology · 2020Article
- Laryngeal vibration as a non-invasive neuromodulation therapy for spasmodic dysphonia.Scientific reports · 2019Article
- Atypical somatosensory-motor cortical response during vowel vocalization in spasmodic dysphonia.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2019Article
- Short Interval Intracortical Inhibition Responses to Low-Frequency Repetitive Transcranial Magnetic Stimulation Under Multiple Interstimulus Intervals and Conditioning Intensities.Neuromodulation : journal of the International Neuromodulation Society · 2018Article
- Evaluation of the Cortical Silent Period of the Laryngeal Motor Cortex in Healthy Individuals.Frontiers in neuroscience · 2017Article
- Cortical sensorimotor alterations classify clinical phenotype and putative genotype of spasmodic dysphonia.European journal of neurology · 2016Article
- Cortical Silent Period Reveals Differences Between Adductor Spasmodic Dysphonia and Muscle Tension Dysphonia.Neurorehabilitation and neural repair · 2016Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The purpose of this study was to compare cortical inhibition in the hand region of the primary motor cortex between subjects with focal hand dystonia (FHD), adductor spasmodic dysphonia (AdSD), and healthy controls. Data from 28 subjects were analyzed (FHD n=11, 53.25 ± 8.74 y; AdSD: n=8, 56.38 ± 7.5 y; and healthy controls: n=941.67 ± 10.85 y). All subjects received single pulse TMS to the left motor cortex to measure cortical silent period (CSP) in the right first dorsal interosseus (FDI) muscle. Duration of the CSP was measured and compared across groups. A one-way ANCOVA with age as a covariate revealed a significant group effect (p<0.001). Post hoc analysis revealed significantly longer CSP duration in the healthy group vs. AdSD group (p<0.001) and FHD group (p<0.001). These results suggest impaired intracortical inhibition is a neurophysiologic characteristic of FHD and AdSD. In addition, the shortened CSP in AdSD provides evidence to support a widespread decrease in cortical inhibition in areas of the motor cortex that represent an asymptomatic region of the body. These findings may inform future investigations of differential diagnosis as well as alternative treatments for focal dystonias.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.