ArticleInternational journal of psychophysiology : official journal of the International Organization of Psychophysiology2014
Auditory event-related potentials and α oscillations in the psychosis prodrome: neuronal generator patterns during a novelty oddball task.
Article in International journal of psychophysiology : official journal of the International Organization of Psychophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- EEG-Based Measures in At-Risk Mental State and Early Stages of Schizophrenia: A Systematic Review.Frontiers in psychiatry · 2021Pooled it
- Event-related modulation of alpha rhythm explains the auditory P300-evoked response in EEG.eLife · 2023Article
- Symptoms of Attenuated Psychosis Syndrome in Relatives of Clinical High-Risk Youth: Preliminary Evidence.Schizophrenia bulletin · 2023Article
- The Role of Alpha Oscillations among the Main Neuropsychiatric Disorders in the Adult and Developing Human Brain: Evidence from the Last 10 Years of Research.Biomedicines · 2022Review
- A quantitative model reveals a frequency ordering of prediction and prediction-error signals in the human brain.Communications biology · 2022Article
- A systematic data-driven approach to analyze sensor-level EEG connectivity: Identifying robust phase-synchronized network components using surface Laplacian with spectral-spatial PCA.Psychophysiology · 2022Article
- Temporal and time-frequency features of auditory oddball response in distinct subtypes of patients at clinical high risk for psychosis.European archives of psychiatry and clinical neuroscience · 2022Article
- Memory Impairments and Psychosis Prediction: A Scoping Review and Theoretical Overview.Neuropsychology review · 2020Article
- Electroencephalography and Event-Related Potential Biomarkers in Individuals at Clinical High Risk for Psychosis.Biological psychiatry · 2020Review
- Evaluation of divided attention using different stimulation models in event-related potentials.Medical & biological engineering & computing · 2019Article
- Target-related parietal P3 and medial frontal theta index the genetic risk for problematic substance use.Psychophysiology · 2019Article
- A Signature of Passivity? An Explorative Study of the N3 Event- Related Potential Component in Passive Oddball Tasks.Frontiers in neuroscience · 2019Article
- Developmental trajectory of mismatch negativity and visual event-related potentials in healthy controls: Implications for neurodevelopmental vs. neurodegenerative models of schizophrenia.Schizophrenia research · 2018Article
- Emotion-Related Consciousness Detection in Patients With Disorders of Consciousness Through an EEG-Based BCI System.Frontiers in human neuroscience · 2018Article
- Neural mechanisms of mismatch negativity dysfunction in schizophrenia.Molecular psychiatry · 2017Article
- Theta- and delta-band EEG network dynamics during a novelty oddball task.Psychophysiology · 2017Article
- Searching for Cross-Diagnostic Convergence: Neural Mechanisms Governing Excitation and Inhibition Balance in Schizophrenia and Autism Spectrum Disorders.Biological psychiatry · 2017Review
- Auditory Target and Novelty Processing in Patients with Unilateral Hippocampal Sclerosis: A Current-Source Density Study.Scientific reports · 2017Article
- Emotion recognition deficits as predictors of transition in individuals at clinical high risk for schizophrenia: a neurodevelopmental perspective.Psychological medicine · 2015Article
- Surface Laplacians (SL) and phase properties of EEG rhythms: Simulated generators in a volume-conduction model.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2015Article
Corrections and comments
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8 authors at 1 institution in 1 country.
Funding
Abstract
Prior research suggests that event-related potentials (ERP) obtained during active and passive auditory paradigms, which have demonstrated abnormal neurocognitive function in schizophrenia, may provide helpful tools in predicting transition to psychosis. In addition to ERP measures, reduced modulations of EEG alpha, reflecting top-down control required to inhibit irrelevant information, have revealed attentional deficits in schizophrenia and its prodromal stage. Employing a three-stimulus novelty oddball task, nose-referenced 48-channel ERPs were recorded from 22 clinical high-risk (CHR) patients and 20 healthy controls detecting target tones (12% probability, 500Hz; button press) among nontargets (76%, 350Hz) and novel sounds (12%). After current source density (CSD) transformation of EEG epochs (-200 to 1000ms), event-related spectral perturbations were obtained for each site up to 30Hz and 800ms after stimulus onset, and simplified by unrestricted time-frequency (TF) principal components analysis (PCA). Alpha event-related desynchronization (ERD) as measured by TF factor 610-9 (spectral peak latency at 610ms and 9Hz; 31.9% variance) was prominent over right posterior regions for targets, and markedly reduced in CHR patients compared to controls, particularly in three patients who later developed psychosis. In contrast, low-frequency event-related synchronization (ERS) distinctly linked to novels (260-1; 16.0%; mid-frontal) and N1 sink across conditions (130-1; 3.4%; centro-temporoparietal) did not differ between groups. Analogous time-domain CSD-ERP measures (temporal PCA), consisting of N1 sink, novelty mismatch negativity (MMN), novelty vertex source, novelty P3, P3b, and frontal response negativity, were robust and closely comparable between groups. Novelty MMN at FCz was, however, absent in the three converters. In agreement with prior findings, alpha ERD and MMN may hold particular promise for predicting transition to psychosis among CHR patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.