ReviewJACC. Cardiovascular imaging2013
The advancing clinical impact of molecular imaging in CVD.
Review in JACC. Cardiovascular imaging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Automated Coronary Optical Coherence Tomography Feature Extraction with Application to Three-Dimensional Reconstruction.Tomography (Ann Arbor, Mich.) · 2022Pooled it
- Myocardial Fibrosis Caused by Angiotensin II Implant in Rabbit Atherosclerosis Model Induced by High Cholesterol Diet.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- Identification and removal of system-induced autofluorescence in miniaturized fiber-optic fluorescence endoscopes.PNAS nexus · 2025Article
- Fibroblast Activation Protein Acts as a Biomarker for Monitoring ECM Remodeling During Aortic Aneurysm viaAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Nitric Oxide in Biomaterial-Based Therapies for Coronary Heart Disease: Mechanistic Insights, Current Advances, and Translational Prospects.Biomaterials research · 2025Review
- Abdominal Aortic Aneurysm and PET/CT: From Molecular Mechanisms to Potential Molecular Imaging Targets.Reviews in cardiovascular medicine · 2023Review
- Article
- Nanotechnology for cardiovascular diseases.Innovation (Cambridge (Mass.)) · 2022Review
- Host-guest interactions of indocyanine green with β-cyclodextrin permit real-time characterization of the rat lymphatic system.JVS-vascular science · 2022Article
- Intravascular Molecular-Structural Assessment of Arterial Inflammation in Preclinical Atherosclerosis Progression.JACC. Cardiovascular imaging · 2021Article
- Highly Selective PPARα (Peroxisome Proliferator-Activated Receptor α) Agonist Pemafibrate Inhibits Stent Inflammation and Restenosis Assessed by Multimodality Molecular-Microstructural Imaging.Journal of the American Heart Association · 2021Article
- Critical review of PET imaging for detection and characterization of the atherosclerotic plaques with emphasis on limitations of FDG-PET compared to NaF-PET in this setting.American journal of nuclear medicine and molecular imaging · 2021Review
- Bimodal Imaging-Visible Nanomedicine Integrating CXCR4 and VEGFa Genes Directs Synergistic Reendothelialization of Endothelial Progenitor Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
- Monitoring Endothelin-A Receptor Expression during the Progression of Atherosclerosis.Biomedicines · 2020Article
- Intra-coronary Imaging for the Evaluation of Plaque Modifications Induced by Drug Therapies for Secondary Prevention.Current atherosclerosis reports · 2020Review
- In Vivo Aortic Magnetic Resonance Elastography in Abdominal Aortic Aneurysm: A Validation in an Animal Model.Investigative radiology · 2020Article
- Biomimetic nanoparticle technology for cardiovascular disease detection and treatment.Nanoscale horizons · 2020Review
- Nanoscale Technologies in Highly Sensitive Diagnosis of Cardiovascular Diseases.Frontiers in bioengineering and biotechnology · 2020Review
- Quantitative imaging biomarkers in nuclear medicine: from SUV to image mining studies. Highlights from annals of nuclear medicine 2018.European journal of nuclear medicine and molecular imaging · 2019Review
- Cardiovascular Imaging and Theranostics in Cardiovascular Pharmacotherapy.European cardiology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Molecular imaging seeks to unravel critical molecular and cellular events in living subjects by providing complementary biological information to current structural clinical imaging modalities. In recent years, molecular imaging efforts have marched forward into the clinical cardiovascular arena, and are now actively illuminating new biology in a broad range of conditions, including atherosclerosis, myocardial infarction, thrombosis, vasculitis, aneurysm, cardiomyopathy, and valvular disease. Development of novel molecular imaging reporters is occurring for many clinical cardiovascular imaging modalities (positron emission tomography, single-photon emission computed tomography, magnetic resonance imaging), as well as in translational platforms such as intravascular fluorescence imaging. The ability to image, track, and quantify molecular biomarkers in organs not routinely amenable to biopsy (e.g., the heart and vasculature) open new clinical opportunities to tailor therapeutics based on a cardiovascular disease molecular profile. In addition, molecular imaging is playing an increasing role in atherosclerosis drug development in phase II clinical trials. Here, we present state-of-the-art clinical cardiovascular molecular imaging strategies, and explore promising translational approaches positioned for clinical testing in the near term.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.