Evidence map›Paper›PMID 24332027›Full record

ArticleImmunity2013

Making sense of HIV innate sensing.

Andrea L Cox, Robert F Siliciano

Abstract readComment
In one paragraph

Article in Immunity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. The role of immunophilins in viral infection.Biochimica et biophysica acta · 2015
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Andrea L CoxDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address: acox@jhmi.edu.
Robert F SilicianoDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Howard Hughes Medical Institute, Baltimore, MD 21201, USA.

Funding

Antibody-Mediated Suppression of Antiviral Inflammasome ActivationR01AI108403 · NIAID · JOHNS HOPKINS UNIVERSITY · PI COX, ANDREA L · 2013 to 2017
$2.2M
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI108403
6 · The paper itself

Abstract

Innate sensing of HIV is important in host control and pathogenesis. In this issue of Immunity, Lahaye et al. (2013) demonstrate that HIV capsid-cyclophilin A interactions affect viral cDNA sensing by the DNA sensor cCAS and contribute to differential pathogenesis of HIV-1 and HIV-2.

Indexed as

Dendritic CellsCapsidCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseDNA, ComplementaryHIV-1HIV-2HIV InfectionsHumansNucleotidyltransferasescGAS protein, humanCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseDNA, ComplementaryNucleotidyltransferases

Identifiers

PMID24332027
PMCPMC4434593

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.