ArticleBMC plant biology2013
Genome-wide characterization of microRNA in foxtail millet (Setaria italica).
Article in BMC plant biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 55 citations in OpenAlex.
- Integrative RNA sequencing uncovers the miRNA-mRNA landscape of water-deficit response in Setaria italica.Planta · 2026Article
- Characterization, functional exploration, and evolutionary analysis of mirtronic microRNAs reveal their origin in the invasive vector mosquito, Aedes albopictus.Insect science · 2026Article
- The miR164b-SiNAC015 Module Regulates Drought Tolerance by Scavenging Reactive Oxygen Species in Foxtail Millet.Plant biotechnology journal · 2026Article
- Review
- Article
- Genome-wide identification of MITE-derived microRNAs and their targets in bread wheat.BMC genomics · 2022Article
- The Construction and Exploration of a Comprehensive MicroRNA Centered Regulatory Network in Foxtail Millet (Frontiers in plant science · 2022Article
- Role of miRNAs in regulation of SA-mediated upregulation of genes involved in folate and methionine metabolism in foxtail millet.Frontiers in plant science · 2022Article
- Newly identified miRNAs may contribute to aerenchyma formation in sugarcane roots.Plant direct · 2020Article
- Structural and Functional Characteristics of miRNAs in Five Strategic Millet Species and Their Utility in Drought Tolerance.Frontiers in genetics · 2020Article
- Drought Response in Rice: The miRNA Story.International journal of molecular sciences · 2019Review
- Analysis of miRNAs and their target genes in five Melilotus albus NILs with different coumarin content.Scientific reports · 2018Article
- Genomic, expressional, protein-protein interactional analysis of Trihelix transcription factor genes in Setaria italia and inference of their evolutionary trajectory.BMC genomics · 2018Article
- Bypassing miRNA-mediated gene regulation under drought stress: alternative splicing affects CSD1 gene expression.Plant molecular biology · 2017Article
- Grasses suppress shoot-borne roots to conserve water during drought.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Combined small RNA and degradome sequencing to identify miRNAs and their targets in response to drought in foxtail millet.BMC genetics · 2016Article
- Article
- Review
- Article
- Global analysis of uncapped mRNA changes under drought stress and microRNA-dependent endonucleolytic cleavages in foxtail millet.BMC plant biology · 2015Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMicroRNAs (miRNAs) are a class of short non-coding, endogenous RNAs that play key roles in many biological processes in both animals and plants. Although many miRNAs have been identified in a large number of organisms, the miRNAs in foxtail millet (Setaria italica) have, until now, been poorly understood.
resultsIn this study, two replicate small RNA libraries from foxtail millet shoots were sequenced, and 40 million reads representing over 10 million unique sequences were generated. We identified 43 known miRNAs, 172 novel miRNAs and 2 mirtron precursor candidates in foxtail millet. Some miRNA*s of the known and novel miRNAs were detected as well. Further, eight novel miRNAs were validated by stem-loop RT-PCR. Potential targets of the foxtail millet miRNAs were predicted based on our strict criteria. Of the predicted target genes, 79% (351) had functional annotations in InterPro and GO analyses, indicating the targets of the miRNAs were involved in a wide range of regulatory functions and some specific biological processes. A total of 69 pairs of syntenic miRNA precursors that were conserved between foxtail millet and sorghum were found. Additionally, stem-loop RT-PCR was conducted to confirm the tissue-specific expression of some miRNAs in the four tissues identified by deep-sequencing.
conclusionsWe predicted, for the first time, 215 miRNAs and 447 miRNA targets in foxtail millet at a genome-wide level. The precursors, expression levels, miRNA* sequences, target functions, conservation, and evolution of miRNAs we identified were investigated. Some of the novel foxtail millet miRNAs and miRNA targets were validated experimentally.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.