ArticleGut pathogens2013
Serogroups, virulence genes and antibiotic resistance in Shiga toxin-producing Escherichia coli isolated from diarrheic and non-diarrheic pediatric patients in Iran.
Article in Gut pathogens, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Antibiotic resistance trends for common bacterial aetiologies of childhood diarrhoea in low- and middle-income countries: A systematic review.Journal of global health · 2023Pooled it
- Prevalence, identification of virulence genes, and antibiotic resistance properties of Shiga-toxin producing Escherichia coli (STEC) strains isolated from ice cream and juice in sales centers.BMC infectious diseases · 2025Article
- Prevalence and Molecular Characterization of Shiga Toxin-ProducingPathogens (Basel, Switzerland) · 2023Article
- Evaluation of the Biological Activity of Laboratory-Prepared Chitosan from Shrimp Shells against Pathogenic Bacterial Isolates.Archives of Razi Institute · 2022Article
- Assessment of well water as a reservoir for extended-spectrum β-lactamases (ESBL) and carbapenem resistantIranian journal of microbiology · 2022Article
- Antibiotic Susceptibility Profiles and Frequency of Resistance Genes in Clinical Shiga Toxin-Producing Escherichia coli Isolates from Michigan over a 14-Year Period.Antimicrobial agents and chemotherapy · 2021Article
- UropathogenicNew microbes and new infections · 2020Article
- Distribution of Antibiotic-ResistantFrontiers in microbiology · 2020Article
- The First Isolation and Molecular Characterization of Shiga Toxin-Producing Virulent Multi-Drug Resistant Atypical EnteropathogenicFrontiers in cellular and infection microbiology · 2019Article
- Prevalence and antimicrobial resistance of shiga toxin-producingIranian journal of microbiology · 2018Article
- Prevalence, identification of virulence factors, O-serogroups and antibiotic resistance properties of Shiga-toxin producingAntimicrobial resistance and infection control · 2018Article
- Review
- Antibiotic resistance, virulence factors and genotyping of UropathogenicAntimicrobial resistance and infection control · 2018Article
- Antibiotic resistance, serogroups, virulence genes, and phylogenetic groups ofGut pathogens · 2017Article
- UropathogenicBioMed research international · 2017Article
- Occurrence ofGut pathogens · 2017Article
- Prevalence, virulence potential, and pulsed-field gel electrophoresis profiling of Shiga toxin-producingGut pathogens · 2017Article
- Shiga (Vero)-toxin producingAntimicrobial resistance and infection control · 2017Article
- Shiga Toxigenic Escherichia coli in Iranian Pediatric Patients With and Without Diarrhea: O-Serogroups, Virulence Factors and Antimicrobial Resistance Properties.Iranian Red Crescent medical journal · 2015Article
- Neem (Azadirachta indica A. Juss) Oil to Tackle Enteropathogenic Escherichia coli.BioMed research international · 2015Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFrom a clinical perspective, it is important to know which serogroups, virulence genes and antibiotic resistance patterns are present in Shiga toxin-producing Escherichia coli strains in pediatric patients suffering from diarrheic and non-diarrheic infections. This is the first study in Iran that has comprehensively investigated the Shiga toxin-producing Escherichia coli -related infection characteristics in diarrheic and non-diarrheic pediatric patients of 0-60 months of age.
methodsTwo-hundred and twenty four diarrheic and 84 non-diarrheic stool specimens were collected from the Baqiyatallah hospital of Tehran, Iran. The stool samples were cultured immediately and those that were E. coli-positive were analyzed for the presence of antibiotic resistance genes and bacterial virulence factors using PCR. Antimicrobial susceptibility testing was performed using disk diffusion method.
resultsOne-hundred and fifty four out of 224 (68.75%) diarrheic stools and 31 out of 84 (36.90%) non-diarrheic stools harbored E. coli. In addition, children in 13-24 month-old age group had the highest incidence of infection with this bacterium (77.63%). A significant difference was found between the frequency of Attaching and Effacing Escherichia coli and Enterohaemorrhagic Escherichia coli (P =0.045). The genes encoding Shiga toxins and intimin were the most commonly detected virulence factors. Among all serogroups studied, O26 (27.04%) and O111 (18.85%) had the highest incidences in the diarrheic and non-diarrheic patients. The incidence of genes encoding resistance against sulfonamide (sul1), gentamicin (aac(3)-IV), trimethoprim (aadA1), cephalothin (blaSHV) and tetracycline (tetA) were 82.78%, 68.03%, 60.65%, 56.55% and 51.63%, respectively. High resistance levels against penicillin (100%), tetracycline (86.88%), gentamicin (62.29%) and streptomycin (54.91%) were observed. Marked seasonality in the serogroup distributions was evident, while STEC infections were more common in summer (P =0.041).
conclusionsOur findings should raise awareness about antibiotic resistance in diarrheic pediatric patients in Iran. Clinicians should exercise caution when prescribing antibiotics, especially during the warmer months of the year.
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Registered trials
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