Evidence map›Paper›PMID 24330568›Full record

Observational studyAddiction science & clinical practice2013

Age and sharing of needle injection equipment in a cohort of Massachusetts injection drug users: an observational study.

Katherine Tassiopoulos, Judith Bernstein, Edward Bernstein

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Addiction science & clinical practice, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01379599 (Brief Intervention to Reduce STDs in ER Drug Users), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01379599 phase3completednot on this map

Brief Intervention to Reduce STDs in ER Drug Users

TypeinterventionalSponsorBoston Medical CenterRan2004 to 2009Enrolled1,030ConditionsSexually Transmitted InfectionArmsbrief motivation intervention
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Summary of available surveillance data on hepatitis C virus infection from eight Arctic countries, 2012 to 2014.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Katherine TassiopoulosDepartment of Epidemiology, Harvard School of Public Health, 677 Huntington Ave,, Boston MA, USA. ktassiop@hsph.harvard.edu.
Judith Bernstein
Edward Bernstein

Funding

Brief Intervention to Reduce STDs in ER Drug UsersR01DA017061 · NIDA · BOSTON MEDICAL CENTER · PI BERNSTEIN, EDWARD BERNSTEIN · 2004 to 2008
$2.5M
NIDA NIH HHS R01 DA017061
6 · The paper itself

Abstract

backgroundHepatitis C infection (HCV) among individuals aged 15-24 years has increased in Massachusetts, likely due to injection drug use. The prevalence of injection equipment sharing (sharing) and its association with age was examined in a cohort of out-of-treatment Massachusetts substance users.

methodsThis analysis included baseline data from a behavioral intervention with substance users. Younger and older (<25 versus ≥ 25 years) injection drug users were compared on demographic characteristics, substance use practices, including factors present during the most recent sharing event ("event-level factors"), and HCV testing history.

resultsSharing was reported by 41% of the 484 individuals who reported injection drug use in the past 30 days. Prevalence of sharing varied by age (50% <25 years old versus 38% ≥ 25 years, p=0.02). In a multivariable logistic regression model younger versus older individuals had twice the odds of sharing (95% CI=1.26, 3.19). During their most recent sharing event, fewer younger individuals than older had their own drugs available (50% versus 75%, p<0.001); other injection event-level factors did not vary by age. In the presence of PTSD, history of exchanging sex for money, or not being US born, prevalence of sharing by older users was higher and was similar to that of younger users, such that there was no association between age and sharing.

conclusionsIn this cohort of injection drug users, younger age was associated with higher prevalence of sharing, but only in the absence of certain stressors. Harm reduction efforts might benefit from intervening on mental health and other stressors in addition to substance use. Study findings suggest a particular need to address the dangers of sharing with young individuals initiating injection drug use.

Indexed as

AdolescentAdultAge FactorsFemaleHepatitis CHIV InfectionsHumansMaleMassachusettsMiddle AgedNeedle SharingPrevalenceSocioeconomic FactorsSubstance Abuse, IntravenousYoung Adult

Identifiers

PMID24330568
PMCPMC3880095

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.