ArticleItalian journal of pediatrics2013
Childhood asthma and vitamin D deficiency in Turkey: is there cause and effect relationship between them?
Article in Italian journal of pediatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- The Role of Vitamin D in Severity and Control of Asthma in Children and Adolescents: A Systematic Review and Meta-Analysis.Pediatric pulmonology · 2026Pooled it
- The serum level of vitamin D and prevalence of vitamin D deficiency among children with asthma in Asia and Africa: a systematic review and meta-analysis.Archives of public health = Archives belges de sante publique · 2024Pooled it
- Vitamin D and asthma in pediatrics: evidence and clinical implications.World journal of pediatrics : WJP · 2025Article
- Research advance in correlation between childhood asthma and gut microbiota.Frontiers in cellular and infection microbiology · 2025Review
- Association of serum vitamin C levels with Asthma in adults: results of NHANES 2003-2006 and mendelian randomization study.BMC pulmonary medicine · 2024Observational
- Application of Metabolomics in Pediatric Asthma: Prediction, Diagnosis and Personalized Treatment.Metabolites · 2021Review
- Association of serum 25-Hydroxyvitamin D with Vitamin D intervention and outdoor activity among children in North China: an observational study.BMC pediatrics · 2020Observational
- Vitamin D deficiency in children with bronchial asthma in southern Jordan: a cross-sectional study.The Journal of international medical research · 2020Article
- Association of 25-hydroxy vitamin D with asthma and its severity in children: a case-control study.Clinical and molecular allergy : CMA · 2020Article
- Association Between Vitamin D Receptor Gene Polymorphism rs2228570 and Allergic Rhinitis.Pharmacogenomics and personalized medicine · 2020Article
- Article
- Predictors of vitamin D status in New Zealand preschool children.Maternal & child nutrition · 2017Article
- The role of vitamin D in allergic rhinitis.Asia Pacific allergy · 2017Review
- The Relationship between Vitamin D Status and Allergic Diseases in New Zealand Preschool Children.Nutrients · 2016Article
- The effect of vitamin D on lower respiratory tract infections in children.Turk pediatri arsivi · 2016Article
- Association between vitamin D deficiency and insufficiency and the risk of childhood asthma: evidence from a meta-analysis.International journal of clinical and experimental medicine · 2015Article
- Association of vitamin D receptor gene polymorphisms and vitamin D levels with asthma and atopy in Cypriot adolescents: a case-control study.Multidisciplinary respiratory medicine · 2015Article
- Vitamin d levels in children with bronchial asthma.Journal of clinical and diagnostic research : JCDR · 2014Article
- Progress in pediatrics in 2013: choices in allergology, endocrinology, gastroenterology, hypertension, infectious diseases, neonatology, neurology, nutrition and respiratory tract illnesses.Italian journal of pediatrics · 2014Review
- Vitamin D and asthma in children: A systematic review and meta-analysis of observational studies.Lung India : official organ of Indian Chest SocietyReview
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpidemiological studies show that vitamin D deficiency and insufficiency are common worldwide and associated with many diseases including asthma. Our aim was to evaluate vitamin D insufficiency and its clinical consequences.
methodsThis cross-sectional study was carried out on 170 children consisted of 85 who were asthmatic and 85 who were not, aged 2 to 14 years in Tekirdag, Turkey, from September 2009 to May 2010. Children's basal serum D vitamin levels were determined, and their eating habits, vitamin D intake, exposure to sunlight and use of health services during the previous year were investigated. The severity of asthma and levels of asthma control were assessed according to the Global Initiative for Asthma guidelines.
resultsThe difference between mean vitamin D levels in the asthmatic group (mean +/- SD) 16.6 +/- 8.5 ng/mL and the healthy control group (mean +/- SD) 28.2 +/- 19.5 ng/mL was found to be statistically significant (p < 0.001). Children in the asthma group had less exposure to sunlight and ate a diet less rich in vitamin D (p < 0.001). A significant difference was observed between the groups regarding the frequency of respiratory tract infections leading to emergency unit admissions and number of hospitalizations (p < 0.001). It was also shown that a decrease in vitamin D level increased the severity of asthma (p < 0.001) and decreased the frequency of controlled asthma (p = 0.010).
conclusionThis study has demonstrated the correlation between plasma 25 (OH) D levels and childhood asthma. Evidently, this relationship being influenced by multiple factors other than vitamin D, further studies should be conducted to explore the interrelation between all such factors.
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