ArticleBMC microbiology2013
Molecular analysis and distribution of multidrug-resistant Enterococcus faecium isolates belonging to clonal complex 17 in a tertiary care center in Mexico City.
Article in BMC microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 33 citations in OpenAlex.
- Comparative core-genome MLST of vancomycin-resistant Enterococcus faecium supports the utility of wastewater-based surveillance: a pilot study.BMC microbiology · 2026Article
- Clinical and microbiological profile of Enterococcus faecium infections in Mexican pediatric patients of a third-level hospital.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Molecular epidemiology, antimicrobial resistance, and virulence determinants of Enterococcus faecium bloodstream isolates: a 7-year study in Shandong, China.BMC microbiology · 2025Article
- Heterogeneity and metabolic diversity amongMicrobiology spectrum · 2025Article
- Molecular characterization of histidine and tyrosine decarboxylating Enterococcus species isolated from some milk products.BMC microbiology · 2025Article
- Molecular characterization and antimicrobial resistance of Enterococcus faecalis isolated from seafood samples.Veterinary medicine and science · 2022Article
- Review
- Current Trends of Enterococci in Dairy Products: A Comprehensive Review of Their Multiple Roles.Foods (Basel, Switzerland) · 2021Review
- Analysis of Vancomycin-Resistant Enterococci in Hemato-Oncological Patients.Antibiotics (Basel, Switzerland) · 2020Article
- Enterococcus faecium: from microbiological insights to practical recommendations for infection control and diagnostics.Antimicrobial resistance and infection control · 2020Review
- Antimicrobial Resistance, Virulence Determinants, and Biofilm Formation ofFrontiers in microbiology · 2019Article
- Genomic confirmation of vancomycin-resistant Enterococcus transmission from deceased donor to liver transplant recipient.PloS one · 2017Article
- Genetic characteristics and molecular epidemiology of vancomycin-resistant Enterococci isolates from Caribbean countries.PloS one · 2017Article
- Molecular Characterization and Resistant Spectrum of Enterococci Isolated from a Haematology Unit in China.Journal of clinical and diagnostic research : JCDR · 2015Article
- Clonal Diversity in Multi Drug Resistant (MDR) Enterococci Isolated from Fecal Normal Flora.International journal of molecular and cellular medicine · 2015Article
- Clonal dissemination of vancomycin-resistant Enterococcus faecium ST412 in a Brazilian region.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
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11 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundEnterococcus faecium has recently emerged as a multidrug-resistant nosocomial pathogen involved in outbreaks worldwide. A high rate of resistance to different antibiotics has been associated with virulent clonal complex 17 isolates carrying the esp and hyl genes and the purK1 allele.
resultsTwelve clinical vancomycin-resistant Enterococcus faecium (VREF) isolates were obtained from pediatric patients at the Hospital Infantil de México Federico Gómez (HIMFG). Among these VREF isolates, 58.3% (7/12) were recovered from urine, while 41.7% (5/12) were recovered from the bloodstream. The VREF isolates showed a 100% rate of resistance to ampicillin, amoxicillin-clavulanate, ciprofloxacin, clindamycin, chloramphenicol, streptomycin, gentamicin, rifampicin, erythromycin and teicoplanin. In addition, 16.7% (2/12) of the isolates were resistant to linezolid, and 66.7% (8/12) were resistant to tetracycline and doxycycline. PCR analysis revealed the presence of the vanA gene in all 12 VREF isolates, esp in 83.3% (10/12) of the isolates and hyl in 50% (6/12) of the isolates. Phylogenetic analysis via molecular typing was performed using pulsed-field gel electrophoresis (PFGE) and demonstrated 44% similarity among the VREF isolates. MLST analysis identified four different sequence types (ST412, ST757, ST203 and ST612).
conclusionThis study provides the first report of multidrug-resistant VREF isolates belonging to clonal complex 17 from a tertiary care center in Mexico City. Multidrug resistance and genetic determinants of virulence confer advantages among VREF in the colonization of their host. Therefore, the prevention and control of the spread of nosocomial infections caused by VREF is crucial for identifying new emergent subclones that could be challenging to treat in subsequent years.
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