Evidence map›Paper›PMID 24330194›Full record

ArticleAddiction biology2015

Emotional graphic cigarette warning labels reduce the electrophysiological brain response to smoking cues.

An-Li Wang, Dan Romer, Igor Elman, Bruce I Turetsky, Ruben C Gur, Daniel D Langleben

Abstract read
In one paragraph

Article in Addiction biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Health Warning Labels for Smokeless Tobacco: The Impact of Graphic Images on Attention, Recall, and Craving.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Advancing Tobacco Product Warning Labels Research Methods and Theory: A Summary of a Grantee Meeting Held by the US National Cancer Institute.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019
    Review
  10. Using Neuroscience to Inform Tobacco Control Policy.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. The Importance of Relevant Emotional Arousal in the Efficacy of Pictorial Health Warnings for Cigarettes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

An-Li WangAnnenberg Public Policy Center, University of Pennsylvania, Philadelphia, PA, USA.
Dan Romer
Igor Elman
Bruce I Turetsky
Ruben C Gur
Daniel D Langleben

Funding

Brain and behavioral effects of graphic cigarette warning labelsR01DA036028 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI LANGLEBEN, DANIEL D · 2013 to 2017
$2.9M
NIDA NIH HHS DA036028NIDA NIH HHS R01 DA036028
6 · The paper itself

Abstract

There is an ongoing public debate about the new graphic warning labels (GWLs) that the Food and Drug Administration (FDA) proposes to place on cigarette packs. Tobacco companies argued that the strongly emotional images FDA proposed to include in the GWLs encroached on their constitutional rights. The court ruled that FDA did not provide sufficient scientific evidence of compelling public interest in such encroachment. This study's objectives were to examine the effects of the GWLs on the electrophysiological and behavioral correlates of smoking addiction and to determine whether labels rated higher on the emotional reaction (ER) scale are associated with greater effects. We studied 25 non-treatment-seeking smokers. Event-related potentials (ERPs) were recorded while participants viewed a random sequence of paired images, in which visual smoking (Cues) or non-smoking (non-Cues) images were preceded by GWLs or neutral images. Participants reported their cigarette craving after viewing each pair. Dependent variables were magnitude of P300 ERPs and self-reported cigarette craving in response to Cues. We found that subjective craving response to Cues was significantly reduced by preceding GWLs, whereas the P300 amplitude response to Cues was reduced only by preceding GWLs rated high on the ER scale. In conclusion, our study provides experimental neuroscience evidence that weighs in on the ongoing public and legal debate about how to balance the constitutional and public health aspects of the FDA-proposed GWLs. The high toll of smoking-related illness and death adds urgency to the debate and prompts consideration of our findings while longitudinal studies of GWLs are underway.

Indexed as

CravingCuesHealth PolicyProduct LabelingAdultBrainEmotionsEvent-Related Potentials, P300FemaleHumansMalePhotic StimulationSmokingAttentional biascigarette cravingevent-related potentialsgraphic cigarette warning labelsP300tobacco control policy

Identifiers

PMID24330194
PMCPMC4492684

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.