Evidence map›Paper›PMID 24329990›Full record

ArticleIndoor air2014

Levels and sources of volatile organic compounds in homes of children with asthma.

J-Y Chin, C Godwin, E Parker, T Robins, T Lewis, P Harbin, S Batterman

Open access · bronzeAbstract read
In one paragraph

Article in Indoor air, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 161 citations in OpenAlex.

  1. Indoor Exposure to Selected Air Pollutants in the Home Environment: A Systematic Review.International journal of environmental research and public health · 2020
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. INdoor Home Air Level Exploration (INHALE) Study: Protocol to Monitor Indoor Pollution in British Dwellings.International journal of environmental research and public health · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. High-throughput UPLC-ESI/MSMS method for simultaneous measurement of the urinary metabolites of volatile organic compounds and tobacco alkaloids.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2025
    Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

J-Y ChinSchool of Public Health, University of Michigan, Ann Arbor, MI, USA.
C Godwin
E Parker
T Robins
T Lewis
P Harbin
S Batterman
University of Michigan–Ann Arbor · USUniversity of Iowa · US

Funding

Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3M
A CBPR Intervention for Childhood Asthma Using Air Filters and Air ConditionersR01ES014566 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEWIS, TOBY C · 2007 to 2011
$3.2M
NIEHS NIH HHS P30 ES017885NIEHS NIH HHS P30ES017885NIEHS NIH HHS R01 ES014566NIEHS NIH HHS R01-ES014566-01A1
6 · The paper itself

Abstract

unlabelledMany volatile organic compounds (VOCs) are classified as known or possible carcinogens, irritants, and toxicants, and VOC exposure has been associated with the onset and exacerbation of asthma. This study characterizes VOC levels in 126 homes of children with asthma in Detroit, Michigan, USA. The total target VOC concentration ranged from 14 to 2274 μg/m(3) (mean = 150 μg/m(3); median = 91 μg/m(3)); 56 VOCs were quantified; and d-limonene, toluene, p, m-xylene, and ethyl acetate had the highest concentrations. Based on the potential for adverse health effects, priority VOCs included naphthalene, benzene, 1,4-dichlorobenzene, isopropylbenzene, ethylbenzene, styrene, chloroform, 1,2-dichloroethane, tetrachloroethene, and trichloroethylene. Concentrations varied mostly due to between-residence and seasonal variation. Identified emission sources included cigarette smoking, solvent-related emissions, renovations, household products, and pesticides. The effect of nearby traffic on indoor VOC levels was not distinguished. While concentrations in the Detroit homes were lower than levels found in other North American studies, many homes had elevated VOC levels, including compounds that are known health hazards. Thus, the identification and control of VOC sources are important and prudent, especially for vulnerable individuals. Actions and policies to reduce VOC exposures, for example, sales restrictions, improved product labeling, and consumer education, are recommended. PRACTICAL IMPLICATIONS: Total target VOC concentrations in the Detroit homes ranged from 14 to 2274 lg/m3, generally lower than found in earlier studies. However, a subset of houses had elevated concentrations, and levels of 1,4-dichlorobenzene, naphthalene, and benzene reached levels commensurate with excess individual cancer risks of 10(-2), 10(-3), and 10(-4), respectively. VOC concentrations varied mostly due to between-residence and season effects. The most important sources included cigarette smoking, vehicle-related emissions, building renovation, solvents, household products, and pesticides.

Indexed as

Air PollutantsAir Pollution, IndoorAsthmaChildEnvironmental ExposureFactor Analysis, StatisticalHousingHumansMichiganRandom AllocationSeasonsUrban PopulationVolatile Organic CompoundsAir PollutantsVolatile Organic CompoundsAsthmaExposureIndoorRiskVolatile organic compounds

Identifiers

PMID24329990
PMCPMC4057989
OpenAlexW2099214822

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.