Evidence map›Paper›PMID 24329966›Full record

Trial reportIndoor air2014

Home interventions are effective at decreasing indoor nitrogen dioxide concentrations.

L M Paulin, G B Diette, M Scott, M C McCormack, E C Matsui, J Curtin-Brosnan, D L Williams, A Kidd-Taylor, M Shea, P N Breysse and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Indoor air, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Indoor Exposure to Selected Air Pollutants in the Home Environment: A Systematic Review.International journal of environmental research and public health · 2020
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Cooking with Natural Gas: Just the Facts, Please.American journal of respiratory and critical care medicine · 2023
    Article
  16. Review
  17. Indoor air pollution exposure is associated with greater morbidity in cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2022
    Article
  18. Article
  19. Article
  20. Obesity may enhance the adverse effects of NOThe Journal of allergy and clinical immunology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

L M PaulinDepartment of Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
G B Diette
M Scott
M C McCormack
E C Matsui
J Curtin-Brosnan
D L Williams
A Kidd-Taylor
M Shea
P N Breysse
N N Hansel
Johns Hopkins University · USJohns Hopkins Medicine · USIn-Q-Tel · USMorgan State University · USSeva Foundation · US

Funding

Oxidative Stress & Inflammation in a Human PM Nasal ChallengeP50ES015903 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI BREYSSE, PATRICK N · 2007 to 2011
$12.1M
The role of obesity in biological responses to particulate matter in miceP50ES018176 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI HANSEL, NADIA N · 2015 to 2019
$4.8M
Project 3: Dissecting the Diet Asthma Relationship in Mice Models of AsthmaP01ES018176 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI BISWAL, SHYAM · 2009 to 2013
$4.2M
Clinical trial of air cleaners to improve indoor air quality and COPD healthR01ES022607 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI HANSEL, NADIA N · 2013 to 2017
$3.4M
Mentoring and Patient Oriented Research in AsthmaK24ES021098 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI DIETTE, GREGORY B · 2012 to 2016
$927k
Domestic endotoxin exposure and chronic obstructive pulmonary diseaseR21ES015781 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI HANSEL, NADIA N · 2008 to 2009
$451k
Peak Indoor NO2 Concentration and Respiratory Outcomes in Children with AsthmaF32ES022115 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI PAULIN, LAURA MARIE · 2012 to 2013
$113k
NIEHS NIH HHS ES015781NIEHS NIH HHS ES015903NIEHS NIH HHS ES018176NIEHS NIH HHS F32 ES022115NIEHS NIH HHS K24 ES021098NIEHS NIH HHS P01 ES018176NIEHS NIH HHS P50 ES015903NIEHS NIH HHS P50 ES018176NIEHS NIH HHS R01 ES022607NIEHS NIH HHS R01ES022607NIEHS NIH HHS R21 ES015781
6 · The paper itself

Abstract

unlabelledNitrogen dioxide (NO2 ), a by-product of combustion produced by indoor gas appliances such as cooking stoves, is associated with respiratory symptoms in those with obstructive airways disease. We conducted a three-armed randomized trial to evaluate the efficacy of interventions aimed at reducing indoor NO2 concentrations in homes with unvented gas stoves: (i) replacement of existing gas stove with electric stove; (ii) installation of ventilation hood over existing gas stove; and (iii) placement of air purifiers with high-efficiency particulate air (HEPA) and carbon filters. Home inspection and NO2 monitoring were conducted at 1 week pre-intervention and at 1 week and 3 months post-intervention. Stove replacement resulted in a 51% and 42% decrease in median NO2 concentration at 3 months of follow-up in the kitchen and bedroom, respectively (P = 0.01, P = 0.01); air purifier placement resulted in an immediate decrease in median NO2 concentration in the kitchen (27%, P < 0.01) and bedroom (22%, P = 0.02), but at 3 months, a significant reduction was seen only in the kitchen (20%, P = 0.05). NO2 concentrations in the kitchen and bedroom did not significantly change following ventilation hood installation. Replacing unvented gas stoves with electric stoves or placement of air purifiers with HEPA and carbon filters can decrease indoor NO2 concentrations in urban homes. PRACTICAL IMPLICATIONS: Several combustion sources unique to the residential indoor environment, including gas stoves, produce nitrogen dioxide (NO2), and higher NO2 concentrations, are associated with worse respiratory morbidity in people with obstructive lung disease. A handful of studies have modified the indoor environment by replacing unvented gas heaters; this study, to our knowledge, is the first randomized study to target unvented gas stoves. The results of this study show that simple home interventions, including replacement of an unvented gas stove with an electric stove or placement of HEPA air purifiers with carbon filters, can significantly decrease indoor NO2 concentrations.

Indexed as

Air PollutantsAir Pollution, IndoorBaltimoreCookingEnvironmental MonitoringHousingHumansNitrogen DioxideStatistics, NonparametricAir PollutantsNitrogen DioxideAir purifierGas stoveHousing interventionIndoor airNitrogen dioxideUrban environment

Identifiers

PMID24329966
PMCPMC4909253
OpenAlexW2119045715

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.