Evidence map›Paper›PMID 24327777›Full record

ArticleThe Korean journal of parasitology2013

Comparison of functional gene annotation of Toxascaris leonina and Toxocara canis using CLC genomics workbench.

Ki Uk Kim, Sang Kyun Park, Shin Ae Kang, Mi Kyung Park, Min Kyoung Cho, Ho-Jin Jung, Kyung-Yun Kim, Hak Sun Yu

Open access · diamondAbstract read
In one paragraph

Article in The Korean journal of parasitology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ki Uk KimDepartment of Internal Medicine, School of Medicine, Pusan National University, Yangsan 626-870, Korea.
Sang Kyun Park
Shin Ae Kang
Mi Kyung Park
Min Kyoung Cho
Ho-Jin Jung
Kyung-Yun Kim
Hak Sun Yu
Pusan National University · KRInsilicogen (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ascarids, Toxocara canis and Toxascaris leonina, are probably the most common gastrointestinal helminths encountered in dogs. In order to understand biological differences of 2 ascarids, we analyzed gene expression profiles of female adults of T. canis and T. leonina using CLC Genomics Workbench, and the results were compared with those of free-living nematode Caenorhabditis elegans. A total of 2,880 and 7,949 ESTs were collected from T. leonina and T. canis, respectively. The length of ESTs ranged from 106 to 4,637 bp with an average insert size of 820 bp. Overall, our results showed that most functional gene annotations of 2 ascarids were quite similar to each other in 3 major categories, i.e., cellular component, biological process, and molecular function. Although some different transcript expression categories were found, the distance was short and it was not enough to explain their different lifestyles. However, we found distinguished transcript differences between ascarid parasites and free-living nematodes. Understanding evolutionary genetic changes might be helpful for studies of the lifestyle and evolution of parasites.

Indexed as

GenomicsAnimalsDog DiseasesDogsFemaleMolecular Sequence AnnotationToxascariasisToxascarisToxocara canisToxocariasisCaenorhabditis elegansCLC genomics workbenchGene ontologyToxascaris leoninaToxocara canis

Identifiers

PMID24327777
PMCPMC3857499
OpenAlexW2073455597

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.