Evidence map›Paper›PMID 24327372›Full record

ArticleJournal of feline medicine and surgery2014

Functional assessment of expiratory flow pattern in feline lower airway disease.

Chung-Hui Lin, Jih-Jong Lee, Chen-Hsuan Liu

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of feline medicine and surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

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  8. Treatment of naturally occurring asthma with inhaled fluticasone or oral prednisolone: A randomized pilot trial.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Chung-Hui LinGraduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taiwan Section of Small Animal Internal Medicine, National Taiwan University Veterinary Hospital, Taiwan.
Jih-Jong LeeGraduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taiwan Section of Small Animal Internal Medicine, National Taiwan University Veterinary Hospital, Taiwan Graduate Institute of Veterinary Clinical Sciences, School of Veterinary Medicine, National Taiwan University, Taiwan.
Chen-Hsuan LiuGraduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taiwan Graduate Institute of Molecular and Comparative Pathobiology, School of Veterinary Medicine, National Taiwan University, Taiwan Section of Diagnostic Pathology, National Taiwan University Veterinary Hospital, Taiwan chhsuliu@ntu.edu.tw.
National Taiwan University Hospital · TWNational Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feline lower airway disease (FLAD) is a chronic respiratory disease of which there is a lack of information on functional assessment in current veterinary medicine. The purposes of this study were to investigate expiratory pattern and evaluate the diagnostic utility of functional parameters in cats with FLAD. Thirty-three client-owned cats (23 FLAD cats and 10 control cats) were studied. Under quiet tidal breathing, pseudo-tidal breathing flow-volume loop (pTBFVL) was obtained from a barometric whole body plethysmography (BWBP) device. There were significant differences in the shapes of expiratory, but not inspiratory, curves between FLAD and control cats. The incidence of the presence of concave expiratory curve indicating lower airway obstruction was 74% in FLAD cats. To assess the diagnostic utility of pTBFVL indices in cats with FLAD, area under the receiver-operator curve was 0.86 for PEF/EF50 (peak expiratory flow divided by expiratory flow at end expiratory volume plus 50% tidal volume); a cuff-off value of PEF/EF50 >1.51 distinguished normal from FLAD (73.9% sensitivity, 100% specificity). There were no significant differences in traditionally measured BWBP parameters (ie, enhanced pause) between cats with and without FLAD in the present study. In conclusion, underlying change on expiratory flow pattern during natural tidal breathing existed in FLAD cats, and selected pTBFVL indices were useful in discriminating FLAD from normal cats. Tidal breathing pattern depicted by pseudoflow-pseudovolume loops from a BWBP system could be a non-invasive tool for functional assessment in client-owned cats.

Indexed as

Tidal VolumeAnimalsCat DiseasesCatsLung Volume MeasurementsPulmonary VentilationReference ValuesRespiratory Tract Diseases

Identifiers

PMID24327372
PMCPMC11164168
OpenAlexW2029577542

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.