Stem cell gene SALL4 in aggressive hepatocellular carcinoma: a cancer stem cell-specific target?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

13 citing papers in PubMed.

1. ADT increases prostate cancer cell invasion via altering AR/SALL4/SOX2-OCT4 stem cell signaling.Cell biology and toxicology · 2025
   Article
2. The new advance of SALL4 in cancer: Function, regulation, and implication.Journal of clinical laboratory analysis · 2023
   Review
3. SALL4 activates PI3K/AKT signaling pathway through targeting PTEN, thus facilitating migration, invasion and proliferation of hepatocellular carcinoma cells.Aging · 2022
   Article
4. SALL4: An Intriguing Therapeutic Target in Cancer Treatment.Cells · 2022
   Review
5. Expression and clinical value of SALL4 in renal cell carcinomas.Molecular medicine reports · 2020
   Article
6. Inflammatory Micro-environment Contributes to Stemness Properties and Metastatic Potential of HCC via the NF-κB/miR-497/SALL4 Axis.Molecular therapy oncolytics · 2019
   Article
7. Upregulation of SALL4 by EGFR activation regulates the stemness of CD44-positive lung cancer.Oncogenesis · 2018
   Article
8. Acquisition of Cholangiocarcinoma Traits during Advanced Hepatocellular Carcinoma Development in Mice.The American journal of pathology · 2018
   Article
9. Human primary liver cancer-derived organoid cultures for disease modeling and drug screening.Nature medicine · 2017
   Article
10. The Recent Advances on Liver Cancer Stem Cells: Biomarkers, Separation, and Therapy.Analytical cellular pathology (Amsterdam) · 2017
    Review
11. Genetic polymorphism of HLA-DQ confers susceptibility to hepatitis B virus-related hepatocellular carcinoma: a case-control study in Han population in China.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Article
12. Tumour antigen expression in hepatocellular carcinoma in a low-endemic western area.British journal of cancer · 2015
    Article
13. Genetic polymorphisms in antioxidant enzyme genes and susceptibility to hepatocellular carcinoma in Chinese population: a case-control study.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015
    Article

Corrections and comments

• Comment on
  Oncofetal gene SALL4 in aggressive hepatocellular carcinoma.2013

Authors and funding

3 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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