ArticleEuropean journal of clinical nutrition2014
Back-transformation of treatment differences--an approximate method.
Article in European journal of clinical nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
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- Differences in the effects of school meals on children's cognitive performance according to gender, household education and baseline reading skills.European journal of clinical nutrition · 2016Trial
- Associations between adiposity, hormones, and gains in height, whole-body height-adjusted bone size, and size-adjusted bone mineral content in 8- to 11-year-old children.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016Trial
- Low-Carbohydrate Diet Patterns That Favor High-Quality Carbohydrates Are Associated with Beneficial Long-Term Changes in Biomarkers of Inflammation and Oxidative Stress in the Framingham Offspring Cohort.Current developments in nutrition · 2025Article
- Long-term outcomes of a Mediterranean diet with or without calorie restriction on cognition and cardiometabolic health: The building research in diet and cognition trial.Preventive medicine reports · 2025Article
- Is underweight associated with poorer diet, nutrient status, bone and cardiometabolic health, and school performance in Danish 8-11-year-olds?European journal of nutrition · 2024Article
- Speed limits: the effects of industrial food processing and food texture on daily energy intake and eating behaviour in healthy adults.European journal of nutrition · 2023Article
- Wholegrain intake, growth and metabolic markers in Danish infants and toddlers: a longitudinal study.European journal of nutrition · 2022Article
- Effect of Mediterranean diet and Mediterranean diet plus calorie restriction on cognition, lifestyle, and cardiometabolic health: A randomized clinical trial.Preventive medicine reports · 2022Article
- Statistical analysis of continuous outcomes from parallel-arm randomized controlled trials in nutrition-a tutorial.European journal of clinical nutrition · 2021Article
- Effect of low energy diet for eight weeks to adults with overweight or obesity on folate, retinol, vitamin BNutrition & metabolism · 2018Article
- Socio-economic differences in cardiometabolic risk markers are mediated by diet and body fatness in 8- to 11-year-old Danish children: a cross-sectional study.Public health nutrition · 2016Article
- Seasonal variations in growth and body composition of 8-11-y-old Danish children.Pediatric research · 2016Observational
- Plate waste and intake of school lunch based on the new Nordic diet and on packed lunches: a randomised controlled trial in 8- to 11-year-old Danish children.Journal of nutritional science · 2015Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesTransformation of outcomes is frequently used in the analysis of studies in clinical nutrition. However, back-transformation of estimated treatment means and differences is complicated by the nonlinear nature of the transformations. It is not straightforward to obtain an estimated treatment difference that can be interpreted without any reference to the additional predictors included in the statistical model; and moreover, standard errors are not easily available. The aim of this work was to provide a generally applicable, yet operational procedure for obtaining back-transformed estimated differences, and corresponding standard errors and 95% confidence intervals. SUBJECTS/
methodsBased on data from two randomized controlled studies and an exemplary data set that had all previously been published, we evaluated our approximate procedure by comparing results for different approaches for showing back-transformed estimated treatment differences.
resultsEstimated differences obtained on logarithm, square root and reciprocal square root-transformed scales were back-transformed into estimated differences on the original scales, and these estimates were in good agreement with the results reported by the original studies.
conclusionsThe proposed approximate procedure provides a flexible approach for obtaining quite accurate back-transformed estimated differences in terms of medians and for deriving the corresponding standard errors.
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Registered trials
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