Evidence map›Paper›PMID 24327110›Full record

ArticleJournal of materials science. Materials in medicine2014

Olive oil based novel thermo-reversible emulsion hydrogels for controlled delivery applications.

Vinay K Singh, Sowmya Ramesh, Kunal Pal, Arfat Anis, Dillip K Pradhan, Krishna Pramanik

Abstract read
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In one paragraph

Article in Journal of materials science. Materials in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
12.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Vinay K SinghDepartment of Biotechnology & Medical Engineering, National Institute of Technology, Rourkela, 769008, Odisha, India, vinay.pharma@gmail.com.
Sowmya Ramesh
Kunal Pal
Arfat Anis
Dillip K Pradhan
Krishna Pramanik
National Institute of Technology Rourkela · INSASTRA University · INSaudi Arabia Basic Industries (Saudi Arabia) · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gels have been considered as a popular mode of delivering medicament for the treatment of sexually transmitted diseases (STDs) (e.g. human immunodeficiency virus, bacterial vaginosis, epididymitis, human papillomavirus infection and condylomata acuminata etc.). The present study discusses the development of novel olive oil based emulsion hydrogels (EHs) using sorbitan monopalmitate as the structuring agent. The developed EHs may be tried as drug delivery vehicle for the treatment of STDs. The formation of EHs was confirmed by fluorescence and confocal microscopy. FTIR studies suggested intermolecular hydrogen bonding amongst the components of the EHs. X-ray diffraction study suggested the amorphous nature of the EHs. The developed EHs have shown non-Newtonian flow behavior. The EHs were found to be biocompatible. The formulations were able to effectively deliver two model antimicrobial drugs (e.g. ciprofloxacin and metronidazole), commonly used in the treatment of the STDs.

Indexed as

Anti-Bacterial AgentsBacillus subtilisCell SurvivalDelayed-Action PreparationsDiffusionEmulsionsHexosesHot TemperatureHydrogelsMaterials TestingOlive OilPlant OilsAnti-Bacterial AgentsDelayed-Action PreparationsEmulsionsHexosesHydrogelsOlive OilPlant Oilssorbitan monopalmitate

Identifiers

PMID24327110
OpenAlexW1999998941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.