Evidence map›Paper›PMID 24326929›Full record

Observational studyClinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine2014

Bone loss over 1 year of training and competition in female cyclists.

Vanessa D Sherk, Daniel W Barry, Karen L Villalon, Kent C Hansen, Pamela Wolfe, Wendy M Kohrt

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04380155 (Effects of Cycling Duration on Markers of Bone Metabolism in Active Young Men), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04380155 nawithdrawnnot on this mapstarted 2023, after this paper: background citation

Effects of Cycling Duration on Markers of Bone Metabolism in Active Young Men

TypeinterventionalSponsorBrock UniversityRan2023 to 2023Enrolled0ConditionsBone Loss, Energy Supply, DeficiencyArmsExercise
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Exercise Early and Often: Effects of Physical Activity and Exercise on Women's Bone Health.International journal of environmental research and public health · 2018
    Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Vanessa D Sherk*Division of Geriatric Medicine, Department of Medicine, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado; †Department of Health, Exercise, and Rehabilitative Sciences, Winona State University, Winona, Minnesota; and ‡Department of Preventative Medicine and Biometrics, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Daniel W Barry
Karen L Villalon
Kent C Hansen
Pamela Wolfe
Wendy M Kohrt
University of Colorado Anschutz Medical Campus · USWinona State University · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025780 · NCRR · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2008 to 2011
$61.3M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
NIDDK National Research Service Award (NRSA) T32 Diversity Administrative SupplementT32DK007658 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Kristen Elizabeth Boyle, Ihuoma U Eneli · 1991 to 2026
$6.0M
COX Inhibition & Musculoskeletal Responses to ExerciseR01AG018857 · NIA · UNIVERSITY OF COLORADO DENVER · PI KOHRT, WENDY M · 2000 to 2010
$4.0M
Response of Trabecular and Cortical Bone to Exercise-Induced Weight LossF32AG035460 · NIA · UNIVERSITY OF COLORADO DENVER · PI SHEA, KAREN L · 2009 to 2011
$114k
NCATS NIH HHS UL1 TR001082NCRR NIH HHS UL1 RR025780NIA NIH HHS F32 AG035460NIA NIH HHS R01 AG018857NIDDK NIH HHS P30 DK048520NIDDK NIH HHS T32 DK007658
6 · The paper itself

Abstract

objectiveTo observe changes in hip, spine, and tibia bone characteristics in female cyclists over the course of 1 year of training.

designProspective observational study.

settingLaboratory.

participantsFemale cyclists (n = 14) aged 26-41 years with at least 1 year of competition history and intent to compete in 10 or more races in the coming year. ASSESSMENT OF RISK FACTORS: Women who train and compete in road cycling as their primary sport.

main outcome measuresTotal body fat-free and fat mass and lumbar spine and proximal femur areal bone mineral density (aBMD) and bone mineral content (BMC) assessments by dual-energy x-ray absorptiometry. Volumetric BMD and BMC of the tibia were measured by peripheral quantitative computed tomography at sites corresponding to 4%, 38%, 66%, and 96% of tibia length. Time points were baseline and after 12 months of training and competition.

resultsWeight and body composition did not change significantly over 12 months. Total hip aBMD and BMC decreased by -1.4% ± 1.9% and -2.1% ± 2.3% (P < 0.02) and subtrochanter aBMD and BMC decreased by -2.1% ± 2.0% and -3.3% ± 3.7% (P < 0.01). There was a significant decrease in lumbar spine BMC (-1.1% ± 1.9%; P = 0.03). There were no significant bone changes in the tibia (P > 0.11).

conclusionsBone loss in female cyclists was site specific and similar in magnitude to losses previously reported in male cyclists. Research is needed to understand the mechanisms for bone loss in cyclists.

Indexed as

AdolescentAdultAthletesBicyclingBone and BonesBone DensityBone ResorptionFemaleHumansMiddle AgedProspective StudiesYoung Adult

Identifiers

PMID24326929
PMCPMC4050043
OpenAlexW1977004985

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.